Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 2796174..2796396 Replicon chromosome
Accession NZ_CP019243
Organism Escherichia coli strain Combat2C1

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag BWI82_RS14430 Protein ID WP_001295224.1
Coordinates 2796174..2796281 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 2796330..2796396 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWI82_RS14405 2791427..2792179 - 753 Protein_2643 cellulose biosynthesis protein BcsQ -
BWI82_RS14410 2792191..2792379 - 189 WP_001063314.1 YhjR family protein -
BWI82_RS14415 2792652..2794223 + 1572 WP_001204945.1 cellulose biosynthesis protein BcsE -
BWI82_RS14420 2794220..2794411 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
BWI82_RS14425 2794408..2796087 + 1680 WP_000191565.1 cellulose biosynthesis protein BcsG -
BWI82_RS14430 2796174..2796281 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 2796330..2796396 + 67 - - Antitoxin
BWI82_RS14445 2796757..2798028 + 1272 WP_001298005.1 amino acid permease -
BWI82_RS14450 2798058..2799062 - 1005 WP_000103577.1 dipeptide ABC transporter ATP-binding subunit DppF -
BWI82_RS14455 2799059..2800042 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
BWI82_RS14460 2800053..2800955 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T71920 WP_001295224.1 NZ_CP019243:c2796281-2796174 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T71920 NZ_CP019243:c2796281-2796174 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT71920 NZ_CP019243:2796330-2796396 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References