Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 326102..326670 Replicon chromosome
Accession NZ_CP019240
Organism Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag RA876_RS01560 Protein ID WP_075585838.1
Coordinates 326102..326392 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RA876_RS01565 Protein ID WP_075585839.1
Coordinates 326380..326670 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RA876_RS01535 321145..322035 - 891 WP_075585835.1 ABC transporter permease -
RA876_RS01540 322022..323176 - 1155 WP_075585836.1 ABC transporter ATP-binding protein -
RA876_RS01545 323317..324384 - 1068 Protein_308 extracellular solute-binding protein -
RA876_RS01550 324599..325414 + 816 WP_075585913.1 TIGR00266 family protein -
RA876_RS01555 325491..326108 + 618 WP_075585837.1 ParA family protein -
RA876_RS01560 326102..326392 - 291 WP_075585838.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RA876_RS01565 326380..326670 - 291 WP_075585839.1 CopG family ribbon-helix-helix protein Antitoxin
RA876_RS01570 326814..329846 - 3033 WP_075585840.1 DNA topoisomerase III -
RA876_RS01575 329998..330396 + 399 WP_139313325.1 SET domain-containing protein-lysine N-methyltransferase -
RA876_RS01580 330403..331215 + 813 WP_075585842.1 biotin--[acetyl-CoA-carboxylase] ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10986.67 Da        Isoelectric Point: 9.5311

>T71890 WP_075585838.1 NZ_CP019240:c326392-326102 [Rhodoferax antarcticus]
MPRLIWSQPALLDLQRLHHFLVTKSPDAAKRAVTAIRQGVRTLALQPRVGRPAEEFPADYREWMIDFGDSGYIALYHFDG
QTAVILAVRHQKELGY

Download         Length: 291 bp

>T71890 NZ_CP019240:c326392-326102 [Rhodoferax antarcticus]
ATGCCACGTCTGATTTGGTCGCAACCAGCACTGCTGGATCTGCAGCGACTTCACCATTTTCTAGTCACCAAAAGTCCTGA
TGCTGCCAAACGCGCCGTAACCGCCATCCGCCAAGGTGTTAGGACACTGGCCCTGCAACCACGCGTAGGCCGACCAGCAG
AGGAGTTTCCTGCAGATTACCGGGAGTGGATGATTGACTTTGGCGACAGCGGCTACATCGCGCTGTACCACTTTGACGGC
CAAACCGCTGTGATTCTGGCGGTGCGGCACCAAAAAGAACTGGGCTACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11017.39 Da        Isoelectric Point: 5.6623

>AT71890 WP_075585839.1 NZ_CP019240:c326670-326380 [Rhodoferax antarcticus]
MTAIVARPVSVKLDQETRGRIDRLATSRRRTTHWLMREAIQQYIEREEKLEAYRQNGIAAWEAYQASGLHVTQEEADAWL
AKLEAGEDVEPPACHV

Download         Length: 291 bp

>AT71890 NZ_CP019240:c326670-326380 [Rhodoferax antarcticus]
ATGACCGCAATCGTTGCCCGACCGGTGTCCGTCAAGCTGGATCAGGAAACGCGTGGCCGGATCGACCGTCTGGCAACTTC
ACGCAGGCGCACCACGCACTGGCTTATGCGCGAAGCCATCCAGCAATACATTGAGCGCGAGGAAAAGCTGGAAGCCTATC
GGCAAAACGGTATCGCAGCCTGGGAGGCCTACCAAGCGTCGGGGCTGCATGTCACGCAGGAAGAAGCGGACGCCTGGCTG
GCAAAACTTGAGGCGGGCGAGGACGTGGAGCCACCTGCATGCCACGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References