Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2395339..2395991 Replicon chromosome
Accession NZ_CP019239
Organism Rhodoferax saidenbachensis strain DSM 22694

Toxin (Protein)


Gene name vapC Uniprot ID A0A1P8KAP8
Locus tag RS694_RS11475 Protein ID WP_029706424.1
Coordinates 2395569..2395991 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1P8KAU0
Locus tag RS694_RS11470 Protein ID WP_029706422.1
Coordinates 2395339..2395572 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS694_RS11460 2391083..2392258 - 1176 WP_081708585.1 glycerophosphodiester phosphodiesterase -
RS694_RS11465 2392506..2395256 + 2751 WP_076069612.1 DEAD/DEAH box helicase -
RS694_RS11470 2395339..2395572 + 234 WP_029706422.1 plasmid stability protein Antitoxin
RS694_RS11475 2395569..2395991 + 423 WP_029706424.1 type II toxin-antitoxin system VapC family toxin Toxin
RS694_RS11480 2396002..2396640 - 639 WP_029706425.1 2'-5' RNA ligase family protein -
RS694_RS11485 2396863..2397996 + 1134 WP_037246745.1 YHYH protein -
RS694_RS11490 2398037..2399398 + 1362 WP_029706427.1 diguanylate cyclase -
RS694_RS11495 2399408..2400340 - 933 WP_029706429.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15071.20 Da        Isoelectric Point: 4.4128

>T71887 WP_029706424.1 NZ_CP019239:2395569-2395991 [Rhodoferax saidenbachensis]
MIILDTNVVSEPLKPEPDPAVLDWLNAQAPETLYITSINLAELLAGVEVLPPGRRRDALGHALLQEVTALFDRRVLSFDA
KAAEFFAKTYASAQAQGNPIGFADCAIAAIAKANGFAIATRNVRDFKGADIDVIDSWTFA

Download         Length: 423 bp

>T71887 NZ_CP019239:2395569-2395991 [Rhodoferax saidenbachensis]
ATGATCATTCTTGACACGAACGTGGTGTCGGAACCGCTAAAGCCCGAACCCGACCCGGCCGTTTTGGACTGGCTCAACGC
CCAAGCACCCGAAACGCTCTACATCACCAGCATCAACCTGGCGGAACTGCTGGCTGGTGTGGAAGTCCTGCCGCCGGGTA
GACGCCGTGATGCGTTGGGACACGCACTGTTGCAAGAAGTGACCGCCCTGTTCGACAGGCGCGTTTTGAGCTTTGATGCG
AAGGCGGCCGAGTTCTTCGCCAAGACCTATGCCAGTGCCCAGGCACAAGGCAACCCCATAGGTTTTGCCGACTGCGCCAT
TGCCGCCATCGCCAAGGCCAACGGATTTGCGATTGCCACGCGCAACGTACGTGATTTCAAAGGCGCAGACATTGACGTGA
TAGATTCCTGGACTTTTGCCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8105.19 Da        Isoelectric Point: 9.1581

>AT71887 WP_029706422.1 NZ_CP019239:2395339-2395572 [Rhodoferax saidenbachensis]
MSSVTVRNLPDATHRALKLRAAQHGRSTEAEIRFILEGAVAPSVGLGSALAAIGRSVGGVDLQTPRDQRPIEPASFE

Download         Length: 234 bp

>AT71887 NZ_CP019239:2395339-2395572 [Rhodoferax saidenbachensis]
ATGTCTTCCGTCACTGTCCGAAACCTCCCCGATGCGACACACCGCGCGCTCAAGCTGCGTGCAGCACAACACGGGCGCAG
CACCGAGGCTGAAATTCGCTTCATTCTGGAAGGTGCCGTGGCCCCAAGCGTCGGTCTGGGTTCCGCGCTGGCTGCCATTG
GCCGCAGTGTGGGCGGGGTCGACCTGCAAACGCCACGTGACCAGCGCCCTATTGAGCCTGCGAGTTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1P8KAP8

Antitoxin

Source ID Structure
AlphaFold DB A0A1P8KAU0

References