71714

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 5459055..5459764 Replicon chromosome
Accession NZ_CP019082
Organism Paludisphaera borealis strain PX4

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag BSF38_RS21045 Protein ID WP_076348936.1
Coordinates 5459375..5459764 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag BSF38_RS21040 Protein ID WP_076348934.1
Coordinates 5459055..5459378 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSF38_RS21025 5455976..5456905 + 930 WP_076348928.1 ABC transporter ATP-binding protein -
BSF38_RS21030 5456940..5458616 + 1677 WP_076348930.1 ABC transporter permease subunit -
BSF38_RS21035 5458634..5458921 - 288 WP_076348932.1 hypothetical protein -
BSF38_RS21040 5459055..5459378 - 324 WP_076348934.1 helix-turn-helix domain-containing protein Antitoxin
BSF38_RS21045 5459375..5459764 - 390 WP_076348936.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSF38_RS21050 5459850..5461241 - 1392 WP_076351237.1 DUF1501 domain-containing protein -
BSF38_RS21055 5461247..5463400 - 2154 WP_076351239.1 DUF1549 and DUF1553 domain-containing protein -
BSF38_RS21060 5463607..5464233 - 627 WP_076348938.1 UbiX family flavin prenyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(22-114)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-84)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14180.30 Da        Isoelectric Point: 10.1196

>T71714 WP_076348936.1 NZ_CP019082:c5459764-5459375 [Paludisphaera borealis]
MSAGEDKSDAKPLEWVGSSLADLKRLPSAVQRRIGHNLYLVQIDTKPMNAKPLSGFGGASVLEIVEDHGGGTYRAVYTVR
FREAVFVLHVFQKKSKKGIKTPKTDVDLIKARLKTASDLYESLYGGEKS

Download         Length: 390 bp

>T71714 NZ_CP019082:c5459764-5459375 [Paludisphaera borealis]
ATGAGTGCGGGCGAGGACAAATCAGACGCCAAGCCGCTGGAGTGGGTGGGGAGCTCACTGGCCGACCTTAAGAGGCTGCC
TAGCGCTGTCCAGAGGCGGATCGGACACAATTTGTACCTGGTCCAGATCGACACGAAGCCCATGAACGCCAAGCCGCTGT
CGGGCTTCGGCGGCGCGAGCGTCCTTGAGATCGTCGAAGACCACGGCGGCGGCACATACCGCGCGGTGTACACGGTGAGG
TTCCGTGAAGCCGTCTTCGTGCTCCACGTCTTCCAGAAGAAGTCGAAGAAGGGAATCAAGACGCCAAAGACCGACGTCGA
CCTGATCAAGGCGCGATTGAAAACGGCGTCGGACCTGTACGAGTCGCTTTACGGGGGCGAAAAATCATGA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11684.51 Da        Isoelectric Point: 11.0436

>AT71714 WP_076348934.1 NZ_CP019082:c5459378-5459055 [Paludisphaera borealis]
MSEPIITRGSTNVFADLGFENAEELLAKSELAAQILKTVRARRLTQAKAGELLGISQPKVSALLNGRLDGFSTDRLFRFL
TKLGWDVQIKLSKAKSKSNGHVRVTSA

Download         Length: 324 bp

>AT71714 NZ_CP019082:c5459378-5459055 [Paludisphaera borealis]
ATGAGCGAGCCCATCATCACTCGCGGCAGCACGAACGTCTTCGCCGACCTGGGGTTCGAGAATGCGGAAGAGTTGCTGGC
CAAGTCCGAACTCGCCGCCCAGATCCTTAAGACCGTCCGCGCCCGGCGGCTGACCCAGGCGAAAGCCGGCGAACTCCTCG
GCATCTCGCAGCCCAAGGTCTCGGCCCTGCTCAACGGCCGACTCGACGGATTCTCGACCGATCGGCTGTTCCGCTTCCTC
ACCAAACTAGGATGGGACGTCCAGATCAAGCTGTCGAAGGCGAAGTCCAAGTCGAACGGCCATGTTCGCGTGACGTCCGC
GTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References