Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1946547..1946692 Replicon chromosome
Accession NZ_CP018438
Organism Klebsiella pneumoniae strain Kp_Goe_822917

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1946583..1946685 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1946547..1946692 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BB746_RS09910 1941677..1943737 + 2061 WP_004151449.1 oligopeptidase B -
BB746_RS09920 1943741..1944400 - 660 WP_032425085.1 exodeoxyribonuclease X -
BB746_RS09925 1944479..1944709 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BB746_RS09930 1944822..1945196 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BB746_RS09935 1945200..1946069 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
BB746_RS09940 1946086..1946424 + 339 WP_016529031.1 YebY family protein -
- 1946547..1946692 - 146 - - Antitoxin
- 1946583..1946685 + 103 - - Toxin
BB746_RS30245 1947060..1947203 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BB746_RS09955 1947308..1948276 - 969 WP_004151446.1 VirK/YbjX family protein -
BB746_RS09960 1948433..1949086 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
BB746_RS09965 1949083..1949274 - 192 WP_002911395.1 YebW family protein -
BB746_RS09970 1949372..1949611 - 240 WP_002911393.1 YebV family protein -
BB746_RS09975 1949727..1951160 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T69996 NZ_CP018438:1946583-1946685 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT69996 NZ_CP018438:c1946692-1946547 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References