Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3262816..3263618 Replicon chromosome
Accession NZ_CP018171
Organism Mesorhizobium oceanicum strain B7

Toxin (Protein)


Gene name TacT3 Uniprot ID A0A1L3STD3
Locus tag BSQ44_RS15910 Protein ID WP_072605893.1
Coordinates 3263091..3263618 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A1L3STF4
Locus tag BSQ44_RS15905 Protein ID WP_072605891.1
Coordinates 3262816..3263094 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSQ44_RS15890 3259651..3260700 - 1050 WP_072605887.1 betaine/proline/choline family ABC transporter ATP-binding protein -
BSQ44_RS15895 3260800..3261753 - 954 WP_072608104.1 ABC transporter substrate-binding protein -
BSQ44_RS15900 3261974..3262738 + 765 WP_072605889.1 DeoR/GlpR family DNA-binding transcription regulator -
BSQ44_RS15905 3262816..3263094 + 279 WP_072605891.1 DUF1778 domain-containing protein Antitoxin
BSQ44_RS15910 3263091..3263618 + 528 WP_072605893.1 GNAT family N-acetyltransferase Toxin
BSQ44_RS15915 3263635..3265251 - 1617 WP_072608105.1 5-guanidino-2-oxopentanoate decarboxylase -
BSQ44_RS15920 3265323..3266171 - 849 WP_072605895.1 amidinotransferase -
BSQ44_RS15925 3266409..3267218 + 810 WP_072605897.1 ABC transporter ATP-binding protein -
BSQ44_RS15930 3267267..3268046 + 780 WP_072605899.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19415.37 Da        Isoelectric Point: 9.9086

>T68865 WP_072605893.1 NZ_CP018171:3263091-3263618 [Mesorhizobium oceanicum]
MTQLAWREEPISKSHDRENFDCGEPHLNDYLRRHARKNHERGASKTFVALSRADERKIVGYYSLSPAALAFQRTPEIIRR
GLARYDVPGFRLGRLAVERGMQGNGLGGQLLLSAARRCILASSEVGGIILLIDAKNEHVAGWYGRYGPIALADEPLSLVL
PLAPIAMLLRSEGKL

Download         Length: 528 bp

>T68865 NZ_CP018171:3263091-3263618 [Mesorhizobium oceanicum]
ATGACACAGCTGGCGTGGCGCGAGGAACCGATCAGCAAATCGCACGACCGGGAGAACTTCGACTGCGGCGAACCACACTT
GAACGACTATCTTCGCCGCCACGCCCGAAAAAATCACGAACGAGGTGCGTCCAAGACGTTTGTCGCCCTGTCGCGCGCAG
ACGAGAGGAAGATCGTCGGCTACTACAGCCTTAGCCCGGCTGCGCTCGCATTCCAGCGCACGCCCGAGATCATCAGGCGC
GGCCTTGCCCGGTACGACGTACCAGGGTTCAGACTCGGCCGATTGGCCGTCGAGCGGGGGATGCAAGGGAACGGCCTGGG
AGGACAATTGCTCCTTTCAGCGGCGCGTCGGTGCATCCTCGCTTCGTCGGAAGTGGGCGGCATCATTCTCCTGATCGACG
CGAAGAACGAGCATGTCGCCGGGTGGTACGGCCGCTATGGCCCGATCGCGCTCGCGGACGAACCTTTGTCCCTCGTGCTT
CCGCTGGCGCCGATCGCCATGCTGCTGCGGTCCGAGGGCAAGCTGTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10432.16 Da        Isoelectric Point: 5.2606

>AT68865 WP_072605891.1 NZ_CP018171:3262816-3263094 [Mesorhizobium oceanicum]
MPRPAVEDNARMSIRIKPRDKATIMRASMLAETDMTDFIIRTAVKAAEELIEKAETTLLTERDSIRVLELLESPPEPNER
MRAAARALPLKE

Download         Length: 279 bp

>AT68865 NZ_CP018171:3262816-3263094 [Mesorhizobium oceanicum]
ATGCCTCGCCCAGCAGTCGAAGACAACGCCCGGATGTCGATCCGCATCAAGCCCCGGGACAAGGCGACGATCATGCGCGC
CTCGATGCTGGCGGAGACGGACATGACGGACTTCATCATACGGACTGCCGTGAAGGCGGCCGAGGAGTTGATCGAGAAGG
CGGAAACCACTCTGCTGACAGAACGAGACAGCATCCGCGTCCTCGAGCTTCTGGAAAGCCCTCCGGAGCCGAACGAGAGA
ATGCGAGCTGCTGCCCGAGCTTTGCCGCTTAAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L3STD3

Antitoxin

Source ID Structure
AlphaFold DB A0A1L3STF4

References