Detailed information of TA system TA068685

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 1283272..1283939
• Replicon: chromosome
• Accession: NZ_CP018095
• Organism: Chelatococcus daeguensis strain TAD1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: BOQ54_RS06120
• Protein ID: WP_071924409.1
• Coordinates: 1283272..1283670 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A840BPX5
• Locus tag: BOQ54_RS06125
• Protein ID: WP_019401460.1
• Coordinates: 1283670..1283939 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BOQ54_RS06095	1279002..1279301	-	300	WP_055459195.1	hypothetical protein	-
BOQ54_RS06100	1279403..1279834	-	432	WP_055459373.1	GNAT family acetyltransferase	-
BOQ54_RS06105	1279858..1281276	-	1419	WP_071923525.1	FAD-binding oxidoreductase	-
BOQ54_RS06110	1281273..1282532	-	1260	WP_083586030.1	class I SAM-dependent RNA methyltransferase	-
BOQ54_RS06115	1282537..1283262	-	726	WP_071923527.1	TlyA family RNA methyltransferase	-
BOQ54_RS06120	1283272..1283670	-	399	WP_071924409.1	type II toxin-antitoxin system VapC family toxin	Toxin
BOQ54_RS06125	1283670..1283939	-	270	WP_019401460.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
BOQ54_RS06130	1284227..1286134	-	1908	WP_083585917.1	1-deoxy-D-xylulose-5-phosphate synthase	-
BOQ54_RS06135	1286228..1287145	-	918	WP_071923529.1	pirin family protein	-
BOQ54_RS06140	1287168..1287419	-	252	WP_071923530.1	exodeoxyribonuclease VII small subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-125)

Antitoxin

• Antitoxin VapB-like (1-81)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14195.07 Da
• Isoelectric Point: 6.4547

>T68685 WP_071924409.1 NZ_CP018095:c1283670-1283272 [Chelatococcus daeguensis]
IVVDTSAFIAMLTNEPEAEALALALYGAGARYVSAVTVYETRVVLLRRGDARYFIPFGNLLTSANLVLHTFDTAQSNLAS
DAYRRFGRGSGHPARLNLGDCASYALAMSLDAPLLYKGNDFSQTDVRSALAT

Nucleotide

• Length: 399 bp

>T68685 NZ_CP018095:c1283670-1283272 [Chelatococcus daeguensis]
ATCGTCGTCGATACGTCGGCCTTCATCGCCATGCTCACCAATGAGCCGGAAGCCGAAGCGCTCGCTCTGGCGCTCTATGG
CGCCGGCGCCCGCTACGTCTCGGCTGTAACGGTCTATGAAACACGGGTCGTCCTGCTGCGGCGAGGCGATGCTCGCTATT
TCATCCCCTTTGGCAATCTGCTCACCAGCGCCAACCTCGTCCTGCACACCTTCGATACGGCTCAGTCCAATCTCGCGAGC
GACGCCTACCGTCGCTTCGGCCGCGGCTCGGGCCATCCGGCCAGGCTCAATCTCGGCGATTGCGCATCCTATGCCCTCGC
CATGTCGCTCGATGCGCCGCTGCTCTATAAGGGCAACGACTTCTCGCAGACGGACGTGCGCTCGGCGCTCGCCACATAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10262.67 Da
• Isoelectric Point: 4.5728

>AT68685 WP_019401460.1 NZ_CP018095:c1283939-1283670 [Chelatococcus daeguensis]
MALNIKSAETERLAREVAALTGETITEAVRKALEMRLEQAREEREKEIARQMAALRVIQEDVRRLGPLPKITKRDFDELW
GELDDGEQE

Nucleotide

• Length: 270 bp

>AT68685 NZ_CP018095:c1283939-1283670 [Chelatococcus daeguensis]
ATGGCCCTCAACATCAAATCCGCCGAGACGGAGCGTCTCGCCCGCGAGGTCGCGGCGCTCACCGGCGAGACGATCACCGA
AGCCGTGCGCAAGGCGCTCGAGATGCGCCTCGAACAGGCGCGGGAGGAACGGGAGAAGGAAATCGCGCGCCAGATGGCCG
CTTTGCGCGTGATTCAGGAGGATGTCCGCCGCCTCGGTCCGCTGCCGAAGATCACAAAGCGTGATTTCGACGAGTTGTGG
GGGGAACTTGACGACGGCGAGCAGGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A840BPX5