Detailed information of TA system TA068081

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 266311..267068
• Replicon: plasmid pCFSAN017963_01
• Accession: NZ_CP017721
• Organism: Salmonella enterica subsp. enterica serovar Minnesota strain CFSAN017963

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: GX95_RS25530
• Protein ID: WP_071624755.1
• Coordinates: 266311..266793 (-)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: GX95_RS25535
• Protein ID: WP_088137314.1
• Coordinates: 266784..267068 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GX95_RS25500	261634..261969	-	336	Protein_255	type II toxin-antitoxin system RelE/ParE family toxin	-
GX95_RS25505	262170..262658	-	489	WP_157719441.1	hypothetical protein	-
GX95_RS25965	262744..262890	-	147	WP_157719442.1	hypothetical protein	-
GX95_RS25970	263022..263192	-	171	WP_157719443.1	hypothetical protein	-
GX95_RS25510	263522..263728	+	207	WP_088137311.1	hypothetical protein	-
GX95_RS25520	264567..264974	+	408	WP_088137312.1	IS200/IS605 family transposase	-
GX95_RS25525	265468..265917	-	450	WP_088137313.1	hypothetical protein	-
GX95_RS25530	266311..266793	-	483	WP_071624755.1	GNAT family N-acetyltransferase	Toxin
GX95_RS25535	266784..267068	-	285	WP_088137314.1	DUF1778 domain-containing protein	Antitoxin
GX95_RS25540	267281..267643	+	363	Protein_264	transposase	-
GX95_RS25545	267656..267811	-	156	Protein_265	CcdB family protein	-
GX95_RS25550	267814..267891	-	78	Protein_266	type II toxin-antitoxin system CcdA family antitoxin	-
GX95_RS25555	267950..268648	-	699	WP_088137316.1	arsenic resistance NADPH-dependent reductase ArsH	-
GX95_RS25560	268735..269055	+	321	WP_088137317.1	As(III)-sensing metalloregulatory transcriptional repressor ArsR	-
GX95_RS25565	269101..270390	+	1290	WP_088137318.1	arsenite efflux transporter membrane subunit ArsB	-
GX95_RS25570	270403..270828	+	426	WP_088137319.1	glutaredoxin-dependent arsenate reductase	-
GX95_RS25575	270846..271427	-	582	WP_088137320.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..280421	280421

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (14-278)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-93)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 23713.45 Da
• Isoelectric Point: 5.5500

>T68081 WP_071624755.1 NZ_CP017721:c266793-266311 [Salmonella enterica subsp. enterica serovar Minnesota]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Nucleotide

• Length: 483 bp

>T68081 NZ_CP017721:c266793-266311 [Salmonella enterica subsp. enterica serovar Minnesota]
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TTT

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 13999.79 Da
• Isoelectric Point: 5.5500

>AT68081 WP_088137314.1 NZ_CP017721:c267068-266784 [Salmonella enterica subsp. enterica serovar Minnesota]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Nucleotide

• Length: 285 bp

>AT68081 NZ_CP017721:c267068-266784 [Salmonella enterica subsp. enterica serovar Minnesota]
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