Detailed information of TA system TA067971

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 2465040..2465593
• Replicon: chromosome
• Accession: NZ_CP017674
• Organism: Microbacterium sp. BH-3-3-3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BJP65_RS11330
• Protein ID: WP_070409216.1
• Coordinates: 2465321..2465593 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BJP65_RS11325
• Protein ID: WP_083285828.1
• Coordinates: 2465040..2465324 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJP65_RS11305	2461289..2462557	+	1269	WP_070409215.1	serine--tRNA ligase	-
BJP65_RS11310	2462554..2463453	+	900	WP_083285826.1	Cof-type HAD-IIB family hydrolase	-
BJP65_RS11315	2463515..2464765	-	1251	WP_083285827.1	DUF2254 domain-containing protein	-
BJP65_RS11325	2465040..2465324	+	285	WP_083285828.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BJP65_RS11330	2465321..2465593	+	273	WP_070409216.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BJP65_RS11335	2465720..2466985	+	1266	WP_055832953.1	LCP family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10292.95 Da
• Isoelectric Point: 10.9613

>T67971 WP_070409216.1 NZ_CP017674:2465321-2465593 [Microbacterium sp. BH-3-3-3]
VNPEYDVVFTRAARRALERDLPEKVAAAAFEFIAGALRRNPRRVGKPLREPLAPLYSARRGGYRVIYLIVDQQLVIEMVS
IAHRRDAYRG

Nucleotide

• Length: 273 bp

>T67971 NZ_CP017674:2465321-2465593 [Microbacterium sp. BH-3-3-3]
GTGAACCCGGAGTACGACGTCGTCTTCACGCGGGCCGCCCGGCGCGCGCTCGAACGAGACCTTCCCGAGAAGGTCGCCGC
TGCGGCATTCGAGTTCATCGCGGGCGCTTTGCGCCGGAACCCGCGGCGAGTGGGCAAGCCGCTGCGAGAGCCGCTCGCGC
CGCTGTACTCCGCTCGCCGCGGCGGGTATCGAGTCATTTACCTGATCGTCGACCAGCAGTTGGTGATCGAAATGGTGTCG
ATCGCGCACCGCCGTGATGCCTATCGCGGGTGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10145.37 Da
• Isoelectric Point: 4.5141

>AT67971 WP_083285828.1 NZ_CP017674:2465040-2465324 [Microbacterium sp. BH-3-3-3]
MTTLSLADARANLSKLVESAVTTHERFDVTRNGDRVAVLLSADDYDALLETVDILSRPDEVAAVREGLADLASGEKSSLE
DVRAAMIRRGRLSS

Nucleotide

• Length: 285 bp

>AT67971 NZ_CP017674:2465040-2465324 [Microbacterium sp. BH-3-3-3]
ATGACCACCCTCTCTCTCGCCGACGCCCGGGCGAACCTGTCGAAGCTGGTCGAGTCGGCCGTCACGACACACGAGCGCTT
CGACGTCACCCGGAACGGTGACCGTGTCGCAGTGCTGCTCAGCGCTGATGACTACGACGCTCTCCTCGAGACGGTCGACA
TTCTCAGCCGCCCGGATGAGGTTGCGGCGGTGCGTGAGGGTCTGGCCGATCTTGCCTCCGGGGAAAAGTCTTCTCTCGAA
GACGTTCGGGCGGCGATGATCCGGCGCGGACGCCTGTCTTCGTGA