Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1480152..1480629 Replicon chromosome
Accession NZ_CP017599
Organism Moorea producens PAL-8-15-08-1

Toxin (Protein)


Gene name - Uniprot ID A0A1D8TMX3
Locus tag BJP34_RS05660 Protein ID WP_070391501.1
Coordinates 1480360..1480629 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1D8TMZ0
Locus tag BJP34_RS05655 Protein ID WP_070391500.1
Coordinates 1480152..1480379 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJP34_RS05645 1476067..1478802 + 2736 WP_070391498.1 DUF3893 domain-containing protein -
BJP34_RS05650 1478802..1479659 + 858 WP_070391499.1 alpha/beta hydrolase -
BJP34_RS42515 1479870..1480046 - 177 WP_158517033.1 hypothetical protein -
BJP34_RS05655 1480152..1480379 - 228 WP_070391500.1 CopG family transcriptional regulator Antitoxin
BJP34_RS05660 1480360..1480629 - 270 WP_070391501.1 BrnT family toxin Toxin
BJP34_RS05665 1480741..1480986 + 246 WP_070391502.1 hypothetical protein -
BJP34_RS05670 1480986..1481408 + 423 WP_070391503.1 type II toxin-antitoxin system VapC family toxin -
BJP34_RS05675 1481872..1482348 - 477 WP_070391504.1 lipocalin-like domain-containing protein -
BJP34_RS05680 1483365..1485077 + 1713 WP_070390566.1 group II intron reverse transcriptase/maturase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(5-69)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10532.85 Da        Isoelectric Point: 9.0292

>T67798 WP_070391501.1 NZ_CP017599:c1480629-1480360 [Moorea producens PAL-8-15-08-1]
VEFEFDDSKSQSNLAKHGINFKEAQQIWDDSNRVEIPARTEDEARFFVIGKIAQKCWSAIITYRQNRVRIISVRRSRKEE
VAIYESNRI

Download         Length: 270 bp

>T67798 NZ_CP017599:c1480629-1480360 [Moorea producens PAL-8-15-08-1]
GTGGAATTTGAATTTGACGACTCTAAAAGCCAATCTAACTTAGCAAAGCACGGAATCAACTTCAAAGAGGCACAACAGAT
ATGGGACGATTCTAATCGAGTGGAAATCCCTGCTCGAACAGAGGACGAAGCGAGATTTTTTGTCATCGGTAAAATCGCTC
AAAAATGCTGGTCAGCCATCATTACCTATCGACAAAACAGAGTACGGATTATCTCAGTCCGGCGATCGCGAAAAGAAGAG
GTAGCCATTTATGAAAGCAACAGAATTTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8783.98 Da        Isoelectric Point: 5.1299

>AT67798 WP_070391500.1 NZ_CP017599:c1480379-1480152 [Moorea producens PAL-8-15-08-1]
MKATEFDAKFDQGEDITEFLDLSHAKRPGYEQKRVNVDFPTWMIEALDREAKRLGVTRQSIIKVWLAERLEQLSS

Download         Length: 228 bp

>AT67798 NZ_CP017599:c1480379-1480152 [Moorea producens PAL-8-15-08-1]
ATGAAAGCAACAGAATTTGATGCCAAATTCGATCAGGGGGAAGACATTACTGAATTCTTAGACCTTTCCCATGCTAAACG
TCCTGGATATGAGCAGAAACGAGTTAATGTTGATTTCCCAACTTGGATGATTGAAGCATTGGATCGGGAAGCAAAACGAT
TGGGGGTCACCCGTCAGTCAATTATTAAAGTATGGCTCGCTGAACGACTTGAACAGCTATCGTCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D8TMX3

Antitoxin

Source ID Structure
AlphaFold DB A0A1D8TMZ0

References