Detailed information of TA system TA066898

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3850459..3850994
• Replicon: chromosome
• Accession: NZ_CP017482
• Organism: Pectobacterium polaris strain NIBIO1392

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BJK05_RS17420
• Protein ID: WP_095701126.1
• Coordinates: 3850459..3850746 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6DB37
• Locus tag: BJK05_RS17425
• Protein ID: WP_010281712.1
• Coordinates: 3850743..3850994 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJK05_RS17400	3845884..3847239	+	1356	WP_095701123.1	alkyl/aryl-sulfatase	-
BJK05_RS17405	3847361..3847744	+	384	WP_095701124.1	TfoX/Sxy family protein	-
BJK05_RS17410	3848034..3848876	+	843	WP_095701125.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
BJK05_RS17415	3849005..3850357	+	1353	WP_010296544.1	glutathione-disulfide reductase	-
BJK05_RS17420	3850459..3850746	-	288	WP_095701126.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BJK05_RS17425	3850743..3850994	-	252	WP_010281712.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BJK05_RS17430	3851249..3852154	+	906	WP_095701127.1	siderophore-interacting protein	-
BJK05_RS17435	3852188..3852943	-	756	WP_095701989.1	thiol:disulfide interchange protein DsbG	-
BJK05_RS17440	3853054..3854094	-	1041	WP_095701128.1	HipA domain-containing protein	-
BJK05_RS17445	3854091..3854405	-	315	WP_095701129.1	HipA N-terminal domain-containing protein	-
BJK05_RS17450	3854390..3854605	-	216	WP_119888975.1	helix-turn-helix transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11061.11 Da
• Isoelectric Point: 10.2540

>T66898 WP_095701126.1 NZ_CP017482:c3850746-3850459 [Pectobacterium polaris]
MSYSIKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSATLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T66898 NZ_CP017482:c3850746-3850459 [Pectobacterium polaris]
ATGAGTTATAGCATCAAATTCAGGGAAGATGCGCTAAAAGAATGGCTCAAGCTCGATAAAACCATTCAGCAGCAATTCGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCCCATATTCCTTCGGCAACGTTACGAGGGATGAAGGACTGCTACAAAATAA
AGCTCCGAGCGTCAGGCTTTCGTTTGGTTTATGAGGTTATTGACGACGTATTGATTATCGCCGTGGTGGCGGTAGGCAAA
CGTGAGCGCAGCGGCGTTTATCATCTGGCGAGTGAGCGAATGAGGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9117.47 Da
• Isoelectric Point: 4.0637

>AT66898 WP_010281712.1 NZ_CP017482:c3850994-3850743 [Pectobacterium polaris]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT66898 NZ_CP017482:c3850994-3850743 [Pectobacterium polaris]
ATGCCGAATATTATATTGAGTGATACCAGTGCCAGCGTCAGTGAGCTGAAAAAGAACCCAATGGCGACGGTCAATGCTGG
CGATGGCCTACCTGTCGCTATCTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGATCAGGAATTGGTTAAGCTGATCGGCGAACGTAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Structures

Antitoxin

• AlphaFold DB: A0A0M2EZP0