Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4152314..4152972 Replicon chromosome
Accession NZ_CP017481
Organism Pectobacterium polaris strain NIBIO1006

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BJJ97_RS18700 Protein ID WP_095994923.1
Coordinates 4152314..4152742 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BJJ97_RS18705 Protein ID WP_095994924.1
Coordinates 4152742..4152972 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ97_RS18680 4148912..4149130 + 219 WP_072012404.1 KTSC domain-containing protein -
BJJ97_RS18685 4149348..4149703 + 356 Protein_3617 hypothetical protein -
BJJ97_RS18690 4149758..4150657 - 900 WP_095994921.1 LysR family transcriptional regulator -
BJJ97_RS18695 4150769..4151782 + 1014 WP_095994922.1 CAR family subclass B3 metallo-beta-lactamase -
BJJ97_RS18700 4152314..4152742 - 429 WP_095994923.1 tRNA(fMet)-specific endonuclease VapC Toxin
BJJ97_RS18705 4152742..4152972 - 231 WP_095994924.1 antitoxin Antitoxin
BJJ97_RS18710 4153065..4153898 - 834 WP_095994925.1 DUF4942 domain-containing protein -
BJJ97_RS18715 4154016..4154336 - 321 WP_095994926.1 TA system toxin CbtA family protein -
BJJ97_RS18720 4154406..4154741 - 336 WP_095994927.1 type IV toxin-antitoxin system YeeU family antitoxin -
BJJ97_RS18725 4154781..4155254 - 474 WP_095994928.1 DNA repair protein RadC -
BJJ97_RS18730 4155340..4155573 - 234 WP_039494636.1 membrane protein -
BJJ97_RS18735 4155590..4156063 - 474 WP_095994929.1 hypothetical protein -
BJJ97_RS18740 4156099..4156668 - 570 WP_095994930.1 hypothetical protein -
BJJ97_RS18745 4156850..4157548 - 699 WP_095994931.1 DeoR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4152314..4165970 13656


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15916.17 Da        Isoelectric Point: 6.7198

>T66889 WP_095994923.1 NZ_CP017481:c4152742-4152314 [Pectobacterium polaris]
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISSITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELARQGTLIGPYDVMLAGHARSAGLILVTNNVREFERVPGLRVDNWVGRSADNNEPL

Download         Length: 429 bp

>T66889 NZ_CP017481:c4152742-4152314 [Pectobacterium polaris]
ATGCTGAAATATCTGCTCGATACCAATATCTGTATTTACACCATCAAGAACAAACCGCAGGAAGTCAGGGACGCTTTCTA
TCGTCATTACGGGCAGTTTGCTATCAGTTCTATCACGCTGATGGAACTGATCTATGGTGCGGAGAAATCGGTAAATCCAG
AAAAGAATCTTGCCGTGATTGAAGGATTTTCTGCGCGTCTGGAAGTGCAAACTTATGGTTTTGACGCTGCCGTACATACC
GGTCAAATTCGGGCGGAACTGGCAAGACAAGGAACACTCATCGGCCCGTATGATGTAATGTTAGCAGGTCATGCGCGGTC
AGCAGGTTTGATACTGGTCACGAACAACGTGCGTGAATTTGAGCGTGTGCCTGGGTTACGAGTAGATAACTGGGTCGGTA
GATCGGCCGACAATAACGAGCCTTTGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8626.68 Da        Isoelectric Point: 4.4091

>AT66889 WP_095994924.1 NZ_CP017481:c4152972-4152742 [Pectobacterium polaris]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEGEGVTSDFMITREQPDDQIREDF

Download         Length: 231 bp

>AT66889 NZ_CP017481:c4152972-4152742 [Pectobacterium polaris]
ATGGAAAAAACTACAGTATTTAAAAGTAACCGCAGCCAGGCGGTACGGCTCCCTAAAGCCGTTGCGCTTCCCGATGATGT
GAAGCAGGTTGATATTGTTGCGATTGGTCGCACACGTATCATCACGCCAGCAGGGGAAAGTTGGGATAGCTGGTTTGAAG
GGGAGGGTGTAACGTCTGATTTCATGATCACCAGAGAGCAGCCTGATGATCAGATCAGGGAAGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References