66817

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1065633..1066413 Replicon chromosome
Accession NZ_CP017454
Organism Dickeya solani strain PPO 9019

Toxin (Protein)


Gene name dhiT Uniprot ID A0A2K8W4P2
Locus tag BJJ98_RS04710 Protein ID WP_022632927.1
Coordinates 1066156..1066413 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID A0A2K8W4X0
Locus tag BJJ98_RS04705 Protein ID WP_022632928.1
Coordinates 1065633..1066148 (-) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ98_RS04680 1061574..1063301 + 1728 WP_022632933.1 hydrogenase large subunit -
BJJ98_RS04685 1063312..1063881 + 570 WP_022632932.1 hydrogenase 4 subunit H -
BJJ98_RS04690 1063878..1064669 + 792 WP_022632931.1 NADH-quinone oxidoreductase subunit B family protein -
BJJ98_RS04695 1064666..1065064 + 399 WP_022632930.1 formate hydrogenlyase maturation HycH family protein -
BJJ98_RS04700 1065057..1065554 + 498 WP_022632929.1 hydrogenase maturation peptidase HycI -
BJJ98_RS04705 1065633..1066148 - 516 WP_022632928.1 DUF2442 domain-containing protein Antitoxin
BJJ98_RS04710 1066156..1066413 - 258 WP_022632927.1 DUF4160 domain-containing protein Toxin
BJJ98_RS04715 1066926..1067468 + 543 WP_022632926.1 4Fe-4S dicluster domain-containing protein -
BJJ98_RS04720 1067503..1069653 + 2151 WP_022632925.1 formate dehydrogenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(80-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10007.56 Da        Isoelectric Point: 8.1243

>T66817 WP_022632927.1 NZ_CP017454:c1066413-1066156 [Dickeya solani]
MPEVDRLAGLIFHLYFYDDERHYLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

>T66817 NZ_CP017454:c1066413-1066156 [Dickeya solani]
ATGCCTGAGGTTGATAGACTGGCAGGGCTAATTTTCCATTTGTACTTTTATGATGATGAGCGGCACTACTTGCCGCATGT
ACATGTCTGCTACGGCAACCATGAGCTGATCATCAGTATTCGTACTGGAACCGAGATCGAAGGATATCTGCCGAATAACA
AGCGCAAGATGGCGCTTGCGCATATCAGGGCCCATCGGGAACAACTGCTGAGTATGTGGGAACGGGCGGTAGTGGGGAGA
AATCCAGGAAAATTGTGA

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 19099.82 Da        Isoelectric Point: 5.2747

>AT66817 WP_022632928.1 NZ_CP017454:c1066148-1065633 [Dickeya solani]
MHKIVEVDVIGDFSLRLTYDDGLVCDINLYQYASSPVFSDVSLFIKFGLLPDGALEWLPDIKISASELRKKGEYVSHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
ELQLEDLQLEE

Download         Length: 516 bp

>AT66817 NZ_CP017454:c1066148-1065633 [Dickeya solani]
ATGCATAAAATCGTGGAAGTTGACGTTATTGGTGATTTTTCGTTGCGCCTGACCTATGACGATGGTCTGGTTTGCGACAT
TAATCTTTATCAATATGCGTCCAGCCCAGTATTTTCGGACGTCAGCCTATTTATCAAGTTTGGGTTGTTGCCGGATGGCG
CGTTGGAATGGCTGCCGGATATTAAGATTTCCGCGTCAGAATTGCGGAAAAAAGGGGAGTATGTCAGCCACACGCTGGCG
GTGCGAGAAAGGCACTTCGCCGATGTCATCTCGCGCGCCTTCTATGATGCCGTGATTGAAAACCGGCCGGAAATTCTGCA
AGCAGCGTTGAAAATCGCGGTGGAAAAACATGGCAACAGCACCGTAGCCAAAGAGGCGGGGGCGAAAAGTCGCACCAGCT
TGTATAAGTCGCTGAATAAAAATACCCATGTCAGCCTGGCGACGGTGGTCAGCCTGGCGCATACCGTGCTGCAGTTGGAA
GAGTTGCAATTGGAAGATCTGCAATTGGAAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W4P2

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W4X0

References