Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3572905..3573163 Replicon chromosome
Accession NZ_CP016358
Organism Escherichia coli strain K-15KW01

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag BA058_RS17500 Protein ID WP_000809168.1
Coordinates 3572905..3573057 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3573106..3573163 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BA058_RS17480 3568150..3568863 - 714 WP_001102393.1 acidic protein MsyB -
BA058_RS17485 3568889..3569293 - 405 WP_000843689.1 DUF2541 family protein -
BA058_RS17490 3569665..3571581 + 1917 WP_000516135.1 molecular chaperone DnaK -
BA058_RS17495 3571670..3572800 + 1131 WP_001118464.1 molecular chaperone DnaJ -
BA058_RS17500 3572905..3573057 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3573106..3573163 + 58 - - Antitoxin
BA058_RS17505 3573672..3574433 + 762 WP_001274828.1 hypothetical protein -
BA058_RS17510 3574453..3575946 + 1494 WP_001314416.1 sulfatase-like hydrolase/transferase -
BA058_RS17515 3576075..3577334 + 1260 WP_000494927.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T64522 WP_000809168.1 NZ_CP016358:c3573057-3572905 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T64522 NZ_CP016358:c3573057-3572905 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT64522 NZ_CP016358:3573106-3573163 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References