Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1266627..1266832 Replicon chromosome
Accession NZ_CP016106
Organism Clostridioides difficile strain DSM 29637

Toxin (Protein)


Gene name CD1233.1 Uniprot ID A0A069A9H6
Locus tag CDIF29637_RS06080 Protein ID WP_009896140.1
Coordinates 1266627..1266779 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name SQ808
Locus tag -
Coordinates 1266759..1266832 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF29637_RS06060 1262089..1262373 - 285 WP_003419254.1 sigma-70 family RNA polymerase sigma factor -
CDIF29637_RS06065 1262396..1263913 - 1518 WP_009896137.1 recombinase family protein -
CDIF29637_RS06070 1264038..1264859 - 822 WP_009896138.1 tetratricopeptide repeat protein -
CDIF29637_RS06075 1265050..1266477 + 1428 WP_021414333.1 cell wall-binding protein Cwp26 -
CDIF29637_RS06080 1266627..1266779 + 153 WP_009896140.1 hypothetical protein Toxin
- 1266759..1266832 - 74 NuclAT_6 - Antitoxin
CDIF29637_RS06085 1268600..1268824 - 225 WP_003438172.1 helix-turn-helix domain-containing protein -
CDIF29637_RS06090 1269503..1269658 + 156 WP_021363414.1 hypothetical protein -
CDIF29637_RS06100 1269904..1270155 + 252 WP_003419270.1 hypothetical protein -
CDIF29637_RS06115 1271375..1271758 - 384 WP_003433385.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5811.96 Da        Isoelectric Point: 11.1039

>T64230 WP_009896140.1 NZ_CP016106:1266627-1266779 [Clostridioides difficile]
MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKFIFKSKK

Download         Length: 153 bp

>T64230 NZ_CP016106:1266627-1266779 [Clostridioides difficile]
ATGGATAACTTTTTGTTTAATGTTTTAGCTAGTTTAACAGCTAGTGTGGTAGTTTACTTAATCAGTAAACTATTCAAAAA
AGCAAAAAGCCACTCTCGCACAAAGAGTGACTTACGAGTTGAATTTAAATTTATATTTAAATCCAAAAAATAA

Antitoxin


Download         Length: 74 bp

>AT64230 NZ_CP016106:c1266832-1266759 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTTGCGTTAGAGTGGAGTTCATCATAAACAGAGTTTATTTTTTGGATTTAAATAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069A9H6

Antitoxin

Download structure file

References