Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1027914..1028177 Replicon chromosome
Accession NZ_CP015379
Organism Hafnia alvei strain HUMV-5920

Toxin (Protein)


Gene name hokH Uniprot ID -
Locus tag A6V27_RS21020 Protein ID WP_071892143.1
Coordinates 1027914..1028072 (-) Length 53 a.a.

Antitoxin (RNA)


Gene name sokH
Locus tag -
Coordinates 1028120..1028177 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6V27_RS04755 1023073..1023606 - 534 WP_063585939.1 SprT family zinc-dependent metalloprotease -
A6V27_RS04760 1024100..1025428 + 1329 WP_025798689.1 cadaverine/lysine antiporter -
A6V27_RS04765 1025534..1027753 + 2220 WP_063585940.1 lysine decarboxylase -
A6V27_RS21020 1027914..1028072 - 159 WP_071892143.1 Hok/Gef family protein Toxin
- 1028120..1028177 + 58 - - Antitoxin
A6V27_RS04770 1028340..1029500 - 1161 WP_025798684.1 glutathionylspermidine synthase family protein -
A6V27_RS04775 1029503..1030186 - 684 WP_040046348.1 DUF1190 family protein -
A6V27_RS04780 1030692..1031792 + 1101 WP_063585941.1 glycerol dehydrogenase -
A6V27_RS04785 1031892..1032962 + 1071 WP_040046350.1 dihydroxyacetone kinase subunit DhaK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-46)


Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6065.37 Da        Isoelectric Point: 9.2226

>T62949 WP_071892143.1 NZ_CP015379:c1028072-1027914 [Hafnia alvei]
MSRKLLLYGLIVMCFTILIFTWMVRGSLCELRIKQGKTEVAAFLNYEDKHAL

Download         Length: 159 bp

>T62949 NZ_CP015379:c1028072-1027914 [Hafnia alvei]
ATGTCGCGTAAGCTGTTGCTTTACGGATTAATAGTAATGTGTTTTACGATATTGATCTTTACCTGGATGGTACGTGGTTC
GCTGTGTGAGCTACGAATTAAGCAGGGAAAAACAGAGGTTGCTGCGTTCTTAAACTACGAAGATAAGCACGCGTTGTAA

Antitoxin


Download         Length: 58 bp

>AT62949 NZ_CP015379:1028120-1028177 [Hafnia alvei]
GTTCAGATGTGGTTAGGATTGCCTCAGGTTAATGAAAATTGACCTGGGGCTTTTACTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References