Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3484146..3484662 Replicon chromosome
Accession NZ_CP015093
Organism Pelagibaca abyssi strain JLT2014

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag Ga0080574_RS20555 Protein ID WP_076703858.1
Coordinates 3484396..3484662 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Ga0080574_RS20550 Protein ID WP_076706083.1
Coordinates 3484146..3484415 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ga0080574_RS20530 3480012..3480446 + 435 WP_076703846.1 CBS domain-containing protein -
Ga0080574_RS20535 3480662..3481153 + 492 WP_076703849.1 pantetheine-phosphate adenylyltransferase -
Ga0080574_RS20540 3481173..3482105 - 933 WP_076703852.1 glycosyltransferase family 2 protein -
Ga0080574_RS20545 3482102..3483877 - 1776 WP_076703855.1 glycosyltransferase family 2 protein -
Ga0080574_RS20550 3484146..3484415 + 270 WP_076706083.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Ga0080574_RS20555 3484396..3484662 + 267 WP_076703858.1 Txe/YoeB family addiction module toxin Toxin
Ga0080574_RS20560 3484677..3484979 - 303 WP_076703861.1 hypothetical protein -
Ga0080574_RS20565 3485122..3486249 + 1128 WP_076703864.1 tRNA guanosine(34) transglycosylase Tgt -
Ga0080574_RS20570 3486417..3487511 + 1095 WP_076703867.1 alkene reductase -
Ga0080574_RS20575 3487587..3487793 - 207 WP_076703870.1 hypothetical protein -
Ga0080574_RS20580 3487786..3488832 - 1047 WP_076703873.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10585.01 Da        Isoelectric Point: 10.2315

>T62330 WP_076703858.1 NZ_CP015093:3484396-3484662 [Pelagibaca abyssi]
MRLIFSDAAWEDYLHWHHTDPKLFQRINALIKEARRSPFHGAGKPEPLRGDLSGWWSRRITREHRMVYRVRGAGEDQSLE
IAQLRYHY

Download         Length: 267 bp

>T62330 NZ_CP015093:3484396-3484662 [Pelagibaca abyssi]
ATGAGGCTGATATTTTCTGATGCAGCCTGGGAAGATTATCTTCACTGGCACCACACCGATCCGAAGCTCTTCCAACGGAT
CAACGCGCTGATAAAAGAAGCGCGCCGATCTCCCTTTCATGGCGCGGGCAAACCCGAACCGCTGAGGGGAGATCTCTCGG
GATGGTGGTCGCGTCGCATAACCCGCGAACACCGCATGGTGTACCGTGTTCGCGGGGCGGGCGAAGACCAATCTCTGGAA
ATCGCGCAGCTTCGTTATCACTACTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10010.21 Da        Isoelectric Point: 4.8452

>AT62330 WP_076706083.1 NZ_CP015093:3484146-3484415 [Pelagibaca abyssi]
MNILTYTDARKHLKAVMDHAIHDKTETVVTRAGQEAVVIVGKEEWDSIQSTLHLLSSPRNAARLRDAIAQLDAEQGRDRD
LIDDEADIF

Download         Length: 270 bp

>AT62330 NZ_CP015093:3484146-3484415 [Pelagibaca abyssi]
ATGAACATCCTGACCTATACGGATGCCCGTAAGCATCTAAAAGCAGTTATGGATCATGCGATCCACGACAAAACCGAAAC
CGTCGTCACGCGCGCGGGGCAGGAGGCTGTGGTGATCGTTGGAAAAGAAGAGTGGGACTCGATCCAATCGACGCTGCACC
TTCTTTCCTCGCCCCGGAACGCCGCCCGGCTGCGGGACGCTATTGCCCAGCTCGACGCCGAGCAGGGCAGAGATCGAGAC
TTGATCGACGATGAGGCTGATATTTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References