Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2759712..2760302 Replicon chromosome
Accession NZ_CP014129
Organism Pantoea vagans strain FDAARGOS_160

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag AL522_RS16935 Protein ID WP_061062835.1
Coordinates 2759712..2760044 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag AL522_RS16940 Protein ID WP_061062836.1
Coordinates 2760045..2760302 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL522_RS16910 2755076..2755708 + 633 WP_061062831.1 TetR family transcriptional regulator -
AL522_RS16915 2755791..2757173 + 1383 WP_061062832.1 FAD-binding protein -
AL522_RS16920 2757186..2758016 + 831 WP_061062833.1 glycosyltransferase family 8 protein -
AL522_RS16925 2758111..2759232 - 1122 WP_061062834.1 Gfo/Idh/MocA family oxidoreductase -
AL522_RS16935 2759712..2760044 - 333 WP_061062835.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
AL522_RS16940 2760045..2760302 - 258 WP_061062836.1 hypothetical protein Antitoxin
AL522_RS16950 2760632..2762809 - 2178 WP_105399988.1 catalase/peroxidase HPI -
AL522_RS16955 2763295..2764317 - 1023 WP_061062839.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-108)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11857.67 Da        Isoelectric Point: 5.8475

>T60224 WP_061062835.1 NZ_CP014129:c2760044-2759712 [Pantoea vagans]
MERGEIWLVTLDPTAGHEQSGKRPVLIVSPASFNAFTRLPIVVPVTSGGNFARAAGFTVSLDGAGCRTKGVIRCDQPGML
DMEAREGRRLEQLPEAIVNEVLARLEAILN

Download         Length: 333 bp

>T60224 NZ_CP014129:c2760044-2759712 [Pantoea vagans]
ATGGAAAGAGGAGAAATCTGGCTGGTGACACTCGACCCCACCGCAGGTCATGAACAAAGTGGGAAGCGTCCGGTATTGAT
CGTTTCTCCGGCCTCGTTTAACGCGTTCACCCGACTACCGATTGTGGTTCCGGTCACCAGTGGCGGAAATTTTGCCCGCG
CAGCGGGTTTTACCGTTTCACTTGATGGGGCAGGGTGCAGGACAAAGGGCGTTATTCGCTGCGATCAGCCGGGGATGCTC
GATATGGAAGCCCGCGAAGGCAGGCGGCTTGAGCAACTACCTGAGGCTATCGTGAATGAAGTGCTGGCACGTCTTGAAGC
CATTCTGAACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9446.98 Da        Isoelectric Point: 5.0349

>AT60224 WP_061062836.1 NZ_CP014129:c2760302-2760045 [Pantoea vagans]
MFITRLKKVGGSIMLTVPPAVLKTLALSINSEVGMTIDNGYLIVKPQYRPRYSLEELLAQCDPHAEMSTEDREWIDAPAA
GKENL

Download         Length: 258 bp

>AT60224 NZ_CP014129:c2760302-2760045 [Pantoea vagans]
ATGTTTATCACGCGTCTTAAAAAGGTTGGCGGATCGATCATGCTGACGGTTCCTCCCGCCGTTCTGAAAACCCTGGCATT
GTCGATAAACAGCGAAGTCGGTATGACTATCGATAATGGTTATCTGATCGTTAAGCCCCAGTATCGTCCGCGATATTCAC
TCGAGGAACTGCTGGCGCAATGCGATCCCCATGCTGAAATGAGCACAGAGGATCGGGAATGGATTGATGCGCCTGCAGCA
GGTAAGGAGAACCTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References