Detailed information of TA system TA059918

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1397489..1398264
• Replicon: chromosome
• Accession: NZ_CP014017
• Organism: Serratia liquefaciens strain FDAARGOS_125

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: AL485_RS06785
• Protein ID: WP_061068906.1
• Coordinates: 1397489..1397857 (-)
• Length: 123 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: AL485_RS06790
• Protein ID: WP_061068907.1
• Coordinates: 1397929..1398264 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AL485_RS06755	1393023..1393442	+	420	WP_020825577.1	DoxX family protein	-
AL485_RS06765	1393993..1394255	-	263	Protein_1317	DNA polymerase III subunit theta	-
AL485_RS25355	1395323..1395481	-	159	WP_020825576.1	hypothetical protein	-
AL485_RS06775	1396224..1397057	-	834	WP_061068904.1	DUF4942 domain-containing protein	-
AL485_RS06780	1397163..1397492	-	330	WP_061068905.1	hypothetical protein	-
AL485_RS06785	1397489..1397857	-	369	WP_061068906.1	TA system toxin CbtA family protein	Toxin
AL485_RS06790	1397929..1398264	-	336	WP_061068907.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
AL485_RS06795	1398276..1398755	-	480	WP_061069160.1	DNA repair protein RadC	-
AL485_RS06800	1398786..1399244	-	459	WP_061068908.1	antirestriction protein	-
AL485_RS06805	1399462..1399818	-	357	WP_061068909.1	hypothetical protein	-
AL485_RS06810	1399880..1400158	-	279	WP_172958975.1	hypothetical protein	-
AL485_RS06815	1400392..1400955	-	564	WP_061068910.1	hypothetical protein	-
AL485_RS06820	1401203..1401958	-	756	WP_061069162.1	50S ribosome-binding GTPase	-
AL485_RS06825	1402583..1403215	+	633	WP_061068911.1	inovirus Gp2 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1388383..1438954	50571

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-111)

Antitoxin

• Antitoxin CbeA (7-107)

Sequences

Toxin

Protein

• Length: 123 a.a.
• Molecular weight: 13892.04 Da
• Isoelectric Point: 8.5011

>T59918 WP_061068906.1 NZ_CP014017:c1397857-1397489 [Serratia liquefaciens]
MKTLPVIPKRAVYSCPTPIAIWRDLLTYLLAQHYGLTVNDTVFSDDTIIQEHIDAGISLADALNFIVEKFDLVRTDRRGF
SCREQSPFITTIDILRARHATGLMTRNGYQVITRTIQGEKRP

Nucleotide

• Length: 369 bp

>T59918 NZ_CP014017:c1397857-1397489 [Serratia liquefaciens]
ATGAAAACTTTACCTGTCATCCCGAAACGGGCGGTTTACTCCTGCCCAACTCCCATTGCGATCTGGCGGGATCTGCTCAC
GTATCTGCTGGCCCAACATTATGGACTGACTGTGAACGACACTGTGTTCAGTGATGACACAATAATTCAGGAACATATTG
ATGCTGGTATATCACTGGCTGATGCTCTGAATTTTATCGTGGAGAAGTTCGACTTGGTACGCACTGACCGGCGGGGGTTC
TCCTGCCGGGAGCAATCACCGTTCATCACTACCATCGATATCTTGCGGGCCCGTCACGCCACCGGGTTGATGACACGTAA
CGGATATCAGGTCATAACACGAACCATTCAGGGAGAAAAACGGCCATGA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12382.11 Da
• Isoelectric Point: 7.9028

>AT59918 WP_061068907.1 NZ_CP014017:c1398264-1397929 [Serratia liquefaciens]
MTSITTPAWGLKRNITPQLGARLVQQGNRLHFLSDRASISGIFSETVARDVDNTVPQFINHLELMLLSGELNPRYQHCVT
LYRNGLTCEADTLGSHGYVYISVYPTRMAAT

Nucleotide

• Length: 336 bp

>AT59918 NZ_CP014017:c1398264-1397929 [Serratia liquefaciens]
ATGACATCTATCACTACCCCAGCCTGGGGACTAAAACGCAACATCACCCCGCAGTTGGGTGCCCGTCTCGTACAGCAAGG
TAACAGGCTCCATTTTCTATCAGACCGCGCCAGTATTAGCGGTATCTTCAGCGAAACGGTGGCCCGAGATGTAGATAATA
CCGTTCCACAGTTTATCAACCACCTGGAGTTGATGTTGTTGTCCGGTGAGCTCAACCCTCGCTATCAGCACTGCGTCACG
CTCTACCGCAATGGGCTGACTTGTGAAGCCGACACATTGGGATCACATGGCTATGTGTATATTTCGGTGTATCCAACGCG
CATGGCAGCCACGTAA