Detailed information of TA system TA059843

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 4813920..4814436
• Replicon: chromosome
• Accession: NZ_CP014007
• Organism: Kosakonia oryzae strain Ola 51

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AWR26_RS22525
• Protein ID: WP_064568651.1
• Coordinates: 4813920..4814204 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AWR26_RS22530
• Protein ID: WP_007372820.1
• Coordinates: 4814194..4814436 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AWR26_RS22510	4809015..4810670	+	1656	WP_064568649.1	alpha,alpha-phosphotrehalase	-
AWR26_RS22515	4811051..4813186	+	2136	WP_064568650.1	anaerobic ribonucleoside-triphosphate reductase	-
AWR26_RS22520	4813449..4813913	+	465	WP_043955374.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
AWR26_RS22525	4813920..4814204	-	285	WP_064568651.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AWR26_RS22530	4814194..4814436	-	243	WP_007372820.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AWR26_RS22535	4814523..4815434	-	912	WP_082934158.1	AraC family transcriptional regulator	-
AWR26_RS22540	4815568..4816401	+	834	WP_064568653.1	oxidoreductase	-
AWR26_RS22545	4816438..4818348	-	1911	WP_064568654.1	BglG family transcription antiterminator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-80)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11117.99 Da
• Isoelectric Point: 10.3168

>T59843 WP_064568651.1 NZ_CP014007:c4814204-4813920 [Kosakonia oryzae]
MTYELVFDPRAYREWEKLGETVRAQFKKKLADVLVQPRIEAARPHDFPDCYKIKLRSSGYRLIYQVCDNVVTVFVIAVGK
REKATAYRHARKRL

Nucleotide

• Length: 285 bp

>T59843 NZ_CP014007:c4814204-4813920 [Kosakonia oryzae]
ATGACCTATGAACTGGTCTTTGATCCGCGGGCATACCGGGAGTGGGAAAAGCTGGGGGAGACAGTAAGAGCGCAATTCAA
AAAGAAACTTGCGGACGTTCTGGTTCAACCACGGATTGAGGCTGCCCGACCGCATGACTTTCCGGATTGCTATAAGATCA
AACTCAGGTCGTCTGGTTACCGGCTGATTTATCAGGTTTGCGATAACGTTGTGACGGTGTTTGTTATCGCTGTGGGAAAG
CGAGAAAAGGCGACCGCTTACCGGCACGCCCGTAAGCGGTTGTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9166.58 Da
• Isoelectric Point: 4.6017

>AT59843 WP_007372820.1 NZ_CP014007:c4814436-4814194 [Kosakonia oryzae]
MATLNVRLDDNLKEEAWTVLEKLNITPTEAVRMLFQYVAENGRMPIKTVTVSDDEEALLKIVRERLANPQKGIRVNLDDL

Nucleotide

• Length: 243 bp

>AT59843 NZ_CP014007:c4814436-4814194 [Kosakonia oryzae]
ATGGCCACGCTAAATGTACGACTGGATGACAATCTCAAGGAAGAGGCCTGGACCGTGCTGGAAAAACTCAATATCACGCC
GACGGAAGCGGTTCGTATGTTGTTTCAGTATGTGGCGGAAAATGGACGTATGCCGATTAAGACCGTGACGGTGAGCGACG
ATGAAGAAGCGCTGTTGAAAATCGTCAGGGAGCGGCTGGCAAATCCGCAGAAAGGCATCAGGGTTAATCTGGATGACCTA
TGA