Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2083717..2084102 Replicon chromosome
Accession NZ_CP012832
Organism Synechocystis sp. PCC 6803 substr. GT-G

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AOY38_RS16760 Protein ID WP_080504056.1
Coordinates 2083998..2084102 (+) Length 35 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag AOY38_RS09885 Protein ID WP_010873096.1
Coordinates 2083717..2084001 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY38_RS09850 2078776..2080611 + 1836 WP_010873091.1 hypothetical protein -
AOY38_RS09855 2080755..2081807 - 1053 WP_010873092.1 2OG-Fe(II) oxygenase -
AOY38_RS09860 2082034..2082261 + 228 WP_020862282.1 DUF2281 domain-containing protein -
AOY38_RS16755 2082307..2082651 + 345 WP_071822655.1 type II toxin-antitoxin system VapC family toxin -
AOY38_RS09870 2082813..2083097 + 285 WP_014407120.1 BrnT family toxin -
AOY38_RS09875 2083102..2083308 + 207 WP_010873094.1 hypothetical protein -
AOY38_RS09880 2083336..2083575 + 240 WP_010873095.1 hypothetical protein -
AOY38_RS09885 2083717..2084001 + 285 WP_010873096.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AOY38_RS16760 2083998..2084102 + 105 WP_080504056.1 type II toxin-antitoxin system YoeB family toxin Toxin
AOY38_RS09890 2084196..2085020 - 825 WP_010873097.1 photosystem II manganese-stabilizing polypeptide -
AOY38_RS09895 2085247..2085624 + 378 WP_010873098.1 hypothetical protein -
AOY38_RS09905 2086021..2086383 - 363 WP_010873099.1 hypothetical protein -
AOY38_RS09910 2086571..2087914 + 1344 WP_010873100.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-32)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(19-83)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 4196.90 Da        Isoelectric Point: 8.5633

>T57270 WP_080504056.1 NZ_CP012832:2083998-2084102 [Synechocystis sp. PCC 6803]
VKLIFSEQAWSDYLYWQQNDKKILKRINTLVELI

Download         Length: 105 bp

>T57270 NZ_CP012832:2083998-2084102 [Synechocystis sp. PCC 6803]
GTGAAGCTAATTTTCTCTGAGCAAGCCTGGAGCGATTATCTTTACTGGCAACAAAACGACAAGAAAATACTTAAAAGAAT
CAATACCTTAGTTGAATTAATTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10540.02 Da        Isoelectric Point: 4.1364

>AT57270 WP_010873096.1 NZ_CP012832:2083717-2084001 [Synechocystis sp. PCC 6803]
MGETLPQQLPNMNAVSQIIAQQKLAAIMEQVCSDHVPTIITRDTQPSVVMISLEDYQSLEETAYLLRSPNNAQKLMSAIK
QLENDQGVERELLE

Download         Length: 285 bp

>AT57270 NZ_CP012832:2083717-2084001 [Synechocystis sp. PCC 6803]
ATGGGGGAAACTTTGCCCCAACAATTGCCAAACATGAACGCAGTCAGCCAAATTATTGCACAACAAAAACTTGCAGCTAT
CATGGAGCAAGTATGTAGTGATCATGTTCCAACAATTATCACCAGGGATACCCAACCATCTGTCGTCATGATTTCCCTGG
AAGACTATCAGTCATTAGAAGAAACAGCATATCTACTACGTAGCCCGAACAATGCTCAAAAATTGATGTCGGCGATCAAG
CAATTAGAAAATGATCAAGGTGTCGAAAGGGAACTATTGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References