Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4589669..4590204 Replicon chromosome
Accession NZ_CP012685
Organism Serratia marcescens strain SmUNAM836

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ABH11_RS21520 Protein ID WP_033649525.1
Coordinates 4589929..4590204 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ABH11_RS21515 Protein ID WP_033649526.1
Coordinates 4589669..4589929 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABH11_RS21495 4584991..4585638 + 648 WP_060446057.1 DcrB-related protein -
ABH11_RS21500 4585679..4586284 + 606 WP_060706920.1 glutathione S-transferase -
ABH11_RS21505 4586354..4587748 + 1395 WP_060706921.1 L-seryl-tRNA(Sec) selenium transferase -
ABH11_RS21510 4587745..4589586 + 1842 WP_033649527.1 selenocysteine-specific translation elongation factor -
ABH11_RS21515 4589669..4589929 + 261 WP_033649526.1 ribbon-helix-helix domain-containing protein Antitoxin
ABH11_RS21520 4589929..4590204 + 276 WP_033649525.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ABH11_RS21525 4590216..4591127 - 912 WP_033636572.1 LysR family transcriptional regulator -
ABH11_RS21530 4591249..4591875 + 627 WP_033649524.1 LysE family translocator -
ABH11_RS21535 4591929..4593176 - 1248 WP_033649577.1 MFS transporter -
ABH11_RS21540 4593394..4594386 + 993 WP_033649523.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10596.34 Da        Isoelectric Point: 10.3377

>T56974 WP_033649525.1 NZ_CP012685:4589929-4590204 [Serratia marcescens]
MELKWTSKALSDLARLFEFLALVNRTAAANSVKALVAAPKALLDNSRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T56974 NZ_CP012685:4589929-4590204 [Serratia marcescens]
ATGGAGTTAAAATGGACGAGTAAGGCGCTATCGGATTTGGCGCGTTTGTTTGAGTTTCTTGCCTTGGTTAACCGTACTGC
GGCAGCGAATTCGGTGAAGGCCTTGGTCGCCGCGCCTAAAGCGTTGCTTGATAATTCTCGCCTGGGTGAAAGACTGGACG
AGTTTTTACCGCAGGAAGTGAGGCGTATTCTGGTCGGCCGTTATGAGATACGTTACCAGGTGCAGCCGGCAACGATTTAT
GTTCTGCGTATTTGGCATACCCGCGAAGAGCGATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9698.01 Da        Isoelectric Point: 4.5201

>AT56974 WP_033649526.1 NZ_CP012685:4589669-4589929 [Serratia marcescens]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALTAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDD
PLPVPR

Download         Length: 261 bp

>AT56974 NZ_CP012685:4589669-4589929 [Serratia marcescens]
ATGAATACGAAAGTCATCACCGCTCATGTCCCGCTGCCTTTGGCTGAAAAGGTGGATGAAATGGCCGCCAAACTTGAACG
CTCACGGGGATGGATAGTGAAGCAAGCCCTCACCGCCTGGCTCGAGCAAGAGGAAGAGCGTCGTCGGTTAACGCTGGCGG
CGCTGGCCGATGTCGAACAGCAAAACGTTATCGATCATGAATCGGTAGAAGCCTGGGCTGCCAGCCTGGACAGTGACGAT
CCGCTGCCGGTACCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References