Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1939600..1940128 Replicon chromosome
Accession NZ_CP012533
Organism Psychrobacter sp. P11G5

Toxin (Protein)


Gene name relE Uniprot ID A0A127GZF7
Locus tag AK825_RS07850 Protein ID WP_068036048.1
Coordinates 1939841..1940128 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A127GZA0
Locus tag AK825_RS07845 Protein ID WP_068036045.1
Coordinates 1939600..1939851 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AK825_RS07830 1935334..1937610 + 2277 WP_068036039.1 ribonucleoside-diphosphate reductase subunit alpha -
AK825_RS07835 1937717..1938274 + 558 WP_068036041.1 hypothetical protein -
AK825_RS07840 1938516..1938866 + 351 WP_068036043.1 hypothetical protein -
AK825_RS07845 1939600..1939851 + 252 WP_068036045.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AK825_RS07850 1939841..1940128 + 288 WP_068036048.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
AK825_RS07855 1940167..1940547 + 381 WP_068039194.1 hypothetical protein -
AK825_RS07860 1940660..1941793 + 1134 WP_068036050.1 ribonucleotide-diphosphate reductase subunit beta -
AK825_RS07865 1942041..1942307 + 267 WP_068036052.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
AK825_RS07870 1942409..1943755 - 1347 WP_068036054.1 trypsin-like peptidase domain-containing protein -
AK825_RS07875 1944104..1944946 + 843 WP_068036055.1 Nif3-like dinuclear metal center hexameric protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-67)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11027.01 Da        Isoelectric Point: 10.7869

>T56615 WP_068036048.1 NZ_CP012533:1939841-1940128 [Psychrobacter sp. P11G5]
MTYNLEFHPLALKEWKKLAPSIQQQFKKKLQQRLLNPRIPASKLSGHTDAYKIKLRTIGYRLVYTVKDDVVVVYVLAVGK
RENNKVYGSLVSRQP

Download         Length: 288 bp

>T56615 NZ_CP012533:1939841-1940128 [Psychrobacter sp. P11G5]
ATGACTTATAATCTTGAGTTTCATCCTTTAGCATTAAAAGAATGGAAAAAGTTAGCGCCCAGTATTCAGCAGCAGTTTAA
GAAAAAATTACAGCAGCGCTTATTAAACCCTCGTATTCCTGCTTCAAAACTCTCAGGACATACAGACGCCTATAAAATCA
AACTACGCACCATAGGCTATCGTCTGGTTTATACCGTCAAAGATGATGTAGTGGTAGTTTATGTGCTAGCCGTAGGCAAA
AGAGAAAACAATAAGGTATATGGAAGCCTTGTGTCGCGCCAACCATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9174.49 Da        Isoelectric Point: 4.2975

>AT56615 WP_068036045.1 NZ_CP012533:1939600-1939851 [Psychrobacter sp. P11G5]
MQPIFATQTASISELKTNPSALIKRSDGESIAILNHNKPVAYLVSTDMYERMMEAMDDMALSQTVDARMNDGQVPVKVTL
DDL

Download         Length: 252 bp

>AT56615 NZ_CP012533:1939600-1939851 [Psychrobacter sp. P11G5]
ATGCAACCGATATTTGCGACACAGACAGCCAGTATCTCAGAACTAAAGACCAACCCTTCGGCACTGATTAAACGGTCGGA
CGGTGAATCCATTGCTATTTTAAATCATAACAAACCTGTGGCTTACTTAGTTTCAACAGATATGTATGAGCGCATGATGG
AAGCGATGGACGATATGGCATTAAGCCAAACCGTTGACGCACGAATGAATGACGGGCAAGTACCTGTAAAGGTAACGTTG
GATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127GZF7

Antitoxin

Source ID Structure
AlphaFold DB A0A127GZA0

References