Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1909295..1909839 Replicon chromosome
Accession NZ_CP012002
Organism Xanthomonas citri pv. aurantifolii strain 1566

Toxin (Protein)


Gene name relE Uniprot ID A0A1U8YMX6
Locus tag AC028_RS08595 Protein ID WP_042675357.1
Coordinates 1909540..1909839 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Z7EKF2
Locus tag AC028_RS08590 Protein ID WP_029818122.1
Coordinates 1909295..1909552 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC028_RS08575 1904428..1905897 - 1470 WP_088411810.1 ribonuclease H-like domain-containing protein -
AC028_RS08580 1905894..1908389 - 2496 WP_007964866.1 DEAD/DEAH box helicase -
AC028_RS08585 1908567..1909229 + 663 WP_029818121.1 hemolysin III family protein -
AC028_RS08590 1909295..1909552 + 258 WP_029818122.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AC028_RS08595 1909540..1909839 + 300 WP_042675357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AC028_RS08605 1910018..1910917 - 900 WP_007964861.1 SDR family NAD(P)-dependent oxidoreductase -
AC028_RS08610 1910977..1911714 - 738 WP_007964860.1 SDR family oxidoreductase -
AC028_RS08615 1911840..1912751 + 912 WP_007964858.1 LysR family transcriptional regulator -
AC028_RS08625 1912966..1914039 - 1074 WP_042675364.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11247.97 Da        Isoelectric Point: 9.7235

>T55403 WP_042675357.1 NZ_CP012002:1909540-1909839 [Xanthomonas citri pv. aurantifolii]
MAEIIWSVPALADLDAIADYTAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T55403 NZ_CP012002:1909540-1909839 [Xanthomonas citri pv. aurantifolii]
ATGGCTGAAATAATCTGGTCAGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACACCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACATCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAAATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9632.12 Da        Isoelectric Point: 8.6223

>AT55403 WP_029818122.1 NZ_CP012002:1909295-1909552 [Xanthomonas citri pv. aurantifolii]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT55403 NZ_CP012002:1909295-1909552 [Xanthomonas citri pv. aurantifolii]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U8YMX6

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7EKF2

References