Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5170398..5170939 Replicon chromosome
Accession NZ_CP011972
Organism Pseudomonas syringae pv. actinidiae ICMP 18884

Toxin (Protein)


Gene name relE Uniprot ID A0A0K8LVV5
Locus tag IYO_RS23255 Protein ID WP_017683357.1
Coordinates 5170664..5170939 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K8LU58
Locus tag IYO_RS23250 Protein ID WP_003382249.1
Coordinates 5170398..5170664 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IYO_RS23235 5165681..5165944 + 264 WP_017683360.1 hypothetical protein -
IYO_RS23240 5166072..5167952 - 1881 WP_003382247.1 methyl-accepting chemotaxis protein -
IYO_RS23245 5168311..5170233 + 1923 WP_017683359.1 methyl-accepting chemotaxis protein -
IYO_RS23250 5170398..5170664 + 267 WP_003382249.1 ribbon-helix-helix domain-containing protein Antitoxin
IYO_RS23255 5170664..5170939 + 276 WP_017683357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IYO_RS23260 5171511..5172779 + 1269 WP_007244158.1 OprD family porin -
IYO_RS23265 5172958..5173782 + 825 WP_003380380.1 NAD(P)-dependent oxidoreductase -
IYO_RS23270 5173842..5174726 + 885 WP_003380378.1 SMP-30/gluconolactonase/LRE family protein -
IYO_RS23275 5174783..5175822 + 1040 Protein_4565 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5146574..5173782 27208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10770.41 Da        Isoelectric Point: 7.0123

>T55305 WP_017683357.1 NZ_CP011972:5170664-5170939 [Pseudomonas syringae pv. actinidiae ICMP 18884]
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T55305 NZ_CP011972:5170664-5170939 [Pseudomonas syringae pv. actinidiae ICMP 18884]
ATGGAGCTGATGTGGACAAGCAAAACGCTATCTGACGTCACCCGCCTGTATGATTTTTTAGCGGTAGCAAACCAGCCCGC
TGCCGCCCAGACCGCACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCGCGGATTGGTGAGCGTCTGGAGG
AGTTTGAGCCCCGGGATGTGCGCAGAATTCAGATAGGCCGCTATGAAATGCGCTACGAAATTGTGGACTCAACAATTTAT
CTGTTGCGGCTGTGGCATACACGCGAGGATCGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9934.24 Da        Isoelectric Point: 5.7066

>AT55305 WP_003382249.1 NZ_CP011972:5170398-5170664 [Pseudomonas syringae pv. actinidiae ICMP 18884]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR

Download         Length: 267 bp

>AT55305 NZ_CP011972:5170398-5170664 [Pseudomonas syringae pv. actinidiae ICMP 18884]
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCGTGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACACCTCTGCCGGTTCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8LVV5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8LU58

References