Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 620501..622080 Replicon chromosome
Accession NZ_CP011957
Organism Xanthomonas oryzae pv. oryzicola strain BXOR1

Toxin (Protein)


Gene name avrRxo1 Uniprot ID A0A5E8KQ48
Locus tag ACU15_RS02740 Protein ID WP_047340211.1
Coordinates 620501..621766 (+) Length 422 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID A0A0C5UZA4
Locus tag ACU15_RS02745 Protein ID WP_044749828.1
Coordinates 621784..622080 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU15_RS23085 617114..617776 + 663 WP_178385938.1 hypothetical protein -
ACU15_RS23090 617773..617991 + 219 WP_076342548.1 immunity protein 31 -
ACU15_RS20800 618037..618153 - 117 Protein_539 IS30 family transposase -
ACU15_RS02730 618199..619647 + 1449 Protein_540 hemagglutinin repeat-containing protein -
ACU15_RS02735 619641..620126 + 486 Protein_541 IS30-like element IS1112a family transposase -
ACU15_RS02740 620501..621766 + 1266 WP_047340211.1 avirulence protein Toxin
ACU15_RS02745 621784..622080 + 297 WP_044749828.1 hypothetical protein Antitoxin
ACU15_RS02750 622302..622568 + 267 Protein_544 transposase -
ACU15_RS02755 622635..623060 - 426 Protein_545 DDE-type integrase/transposase/recombinase -
ACU15_RS02765 623129..624231 + 1103 WP_154235785.1 IS3 family transposase -
ACU15_RS23095 624261..624338 + 78 Protein_547 anti-sigma factor antagonist -
ACU15_RS20805 624433..624608 + 176 Protein_548 HAD family hydrolase -
ACU15_RS02770 624824..625576 - 753 WP_024712407.1 YceI family protein -
ACU15_RS02775 625787..626377 - 591 WP_014504809.1 malonic semialdehyde reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 617773..632011 14238
- inside IScluster/Tn - - 619713..624231 4518


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(149-291)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 422 a.a.        Molecular weight: 45159.73 Da        Isoelectric Point: 6.9140

>T55257 WP_047340211.1 NZ_CP011957:620501-621766 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAATHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI

Download         Length: 1266 bp

>T55257 NZ_CP011957:620501-621766 [Xanthomonas oryzae pv. oryzicola]
ATGAAAAACAAGACAGACATTGCTGGCATAGCCGGACTTTCTACGTCTCATGTTTCCTTTGATGACGCAGAATCCAAAAG
CGTCCTAGATGGATCAACACAGTCTACGCCGGAGTACAAATTCCAGACCCCGCTTGATCAGTTGCCGGCTAGGCCCGCTG
GTCCGAAGAGCAGTAACACAACTGATGCTTACATTCATGAATCACTGCCGCATTCGGTTCCAATCGCAGGTGCATCGACC
TCCGCGGCGACACATCAACAGGCTACTCAGCGTAAAGGCACCGATGAGATCTATGGTTTGGGCAGCCTCCCATCTGCTGG
TCCAGAGCGATGGGATTATCTTGCGAATCCGGGGAACTGGCATCCCGAACGCCGTAAGTTACACGAAAAGCTATTAGATC
AAGCGCGATCTTCTGCCTTGACCCTGGCAGAATCCCTTGAGAGTGATGGCTGCCAACCGACATTGTTTGCGCTGCGCGGA
AATACCGCAACGGGTAAAACACGGATTGCGACAAAAAAGATCCCGGTGCTCGCAGCAGCTCTGAAGAAGACAGGTGGGAA
AGGTTGCGTGAATCCAGATGTATTCAAGAGTTCGCTTGCGAAATCCGAGGCAGGCGCCAAGATATTTAGTTCGGCACAAG
TGCATAGCGAGTCATCTTTTCTTGCCGACCGGTTTGAAGGCGGACTTCGCTCTCAAAAGACGGGCAGCGGTGCAATCGCT
AGCATTGTTGTCGACAAGCGCTTGTCAAGAGCGTACGAAATTGATAGCTACATACAACTAGCGAAAGAAACCGGTAGAAA
AGTGGAATTGTGCGATATCGACGCGCCCCTAGAGAATTCTTTGGTGGGAGTTTTGCAGCGAAAACCGGAAGGTGAAGATC
CTAGGCCTCCGTACCCTGTAGTCTCGAGTGGATTTGTAGCCGTACGGAGCAATAGAATGTACGTGATAGACAGGTTCATT
GCCGATCCGAGCCTGGGAAACTACCGACTATTCGGAACAGCTGAAGATGGTGAGAAGGTCATGGTTGCTAGCGTGATTGG
CGGTGAGTTTAGTGTAGAGAATGCTGAGTTGTATGAAAAAATCACGTCCCCACAGCTCTCGGTTACGGGCGATTTGGCTG
ATAAGGTAATCGACAAGGAATTGATTGATCGTCTGAAAAATAATATAGCTGACCCCGAGCGGGCGGCCAAGACGCAAGCC
GCCCTGGAAAAATACAGCGGTAAGTCATGGTCGGCCGCGCTAGCTGCTCACAGCGAGCTAATTTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11327.83 Da        Isoelectric Point: 5.2138

>AT55257 WP_044749828.1 NZ_CP011957:621784-622080 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS

Download         Length: 297 bp

>AT55257 NZ_CP011957:621784-622080 [Xanthomonas oryzae pv. oryzicola]
ATGAAAACTTTGACAGGCGCAGACGCACTCGAATTTCATAAGAAGCTTAAGGAACGTAATAAAGCCTTACATGCTTCCGA
CCTCGAGTTAGCACTGGTGCACGCCGATGCTGTCGGCAAAGAACGGTTCGATCTCGAGGAGCTGGAGAAAATTTGCGATA
CCAGCGATGCGGGGCGCCTTACTGATGCGAAAGAGCGACACGACATATATGAAAGGATGTACTACGTTGAGTATCCCAAC
GTTATGACGTTAAAGGAATTCGCTCATATCGTCGAGACACTTTCCTCGTGGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5E8KQ48

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5UZA4

References