Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1213568..1215413 Replicon chromosome
Accession NZ_CP011807
Organism Pandoraea faecigallinarum strain DSM 23572

Toxin (Protein)


Gene name doc Uniprot ID A0A0H3WY29
Locus tag AB870_RS05490 Protein ID WP_047907240.1
Coordinates 1213568..1214485 (+) Length 306 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag AB870_RS05495 Protein ID WP_047908838.1
Coordinates 1214550..1215413 (+) Length 288 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB870_RS05465 1208925..1210001 + 1077 WP_047908835.1 porin -
AB870_RS05470 1210403..1211176 + 774 WP_053059744.1 ABC transporter ATP-binding protein -
AB870_RS05475 1211238..1212020 + 783 WP_047907238.1 ABC transporter permease -
AB870_RS05480 1212056..1212847 + 792 WP_047908837.1 SDR family oxidoreductase -
AB870_RS05485 1212898..1213455 + 558 WP_047907239.1 cupin domain-containing protein -
AB870_RS05490 1213568..1214485 + 918 WP_047907240.1 alpha/beta fold hydrolase Toxin
AB870_RS05495 1214550..1215413 + 864 WP_047908838.1 IclR family transcriptional regulator Antitoxin
AB870_RS05500 1215410..1216225 + 816 WP_047907241.1 SDR family oxidoreductase -
AB870_RS05505 1216218..1217870 + 1653 WP_047908839.1 thiamine pyrophosphate-binding protein -
AB870_RS05510 1217863..1218681 + 819 WP_047907242.1 aspartate dehydrogenase -
AB870_RS05515 1218695..1220191 + 1497 WP_047907243.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(58-291)

Antitoxin

Transcription regulator IclR, C-terminal

(142-265)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 31716.90 Da        Isoelectric Point: 5.8926

>T55060 WP_047907240.1 NZ_CP011807:1213568-1214485 [Pandoraea faecigallinarum]
MQAEVIQSEVPEDDAAVAPLRARLDVFPYRTVATRAGTVGYRCAGTGNDAALPVVMQHGIGSGAASWVAQFDATGLDAKL
YAWDAPGYGATSNVADAEPHADAYADALEAWLDALGLDRVALVGHSLGAIMATKLASRAPHRVRGVFLCSPANGYGKAHG
DVRASKRDNRLAMLDKLGPAGMARERSDNLVAPQAAELPRAWVKWNMARVLPAGYRQATHLLSNGDVAGELAQYVRAAAG
AAVVAVAVGAQDGITPPAACEEIARVAGVPLQIIEGAGHASYIETPDVLNAALAAWLERIAAGER

Download         Length: 918 bp

>T55060 NZ_CP011807:1213568-1214485 [Pandoraea faecigallinarum]
ATGCAAGCCGAAGTCATACAGTCCGAAGTGCCCGAAGACGATGCCGCCGTAGCGCCGTTGCGTGCGCGGCTCGACGTCTT
CCCCTATCGCACCGTCGCCACGCGCGCAGGGACCGTCGGCTATCGCTGCGCGGGGACCGGGAACGACGCCGCGCTGCCGG
TTGTGATGCAGCACGGTATCGGCTCCGGCGCGGCGTCGTGGGTCGCGCAATTCGACGCGACCGGCCTGGACGCCAAGTTG
TACGCGTGGGACGCGCCCGGCTATGGCGCGACGTCCAACGTCGCCGACGCCGAGCCGCATGCCGATGCCTACGCCGATGC
GCTCGAAGCGTGGCTCGACGCGCTGGGGCTGGATCGCGTCGCCCTGGTCGGCCATTCGCTGGGCGCGATCATGGCGACGA
AATTGGCAAGCCGCGCACCGCATCGCGTGCGCGGTGTCTTTCTTTGCTCGCCCGCCAACGGTTACGGCAAAGCGCACGGC
GACGTGCGTGCATCGAAGCGCGACAACCGTCTGGCGATGCTCGACAAGCTCGGTCCGGCGGGCATGGCGCGCGAGCGCAG
CGACAACCTCGTCGCACCGCAGGCCGCCGAACTGCCGCGGGCCTGGGTCAAATGGAACATGGCGCGCGTGCTGCCCGCCG
GCTACCGTCAGGCGACGCATCTGCTCTCGAATGGCGATGTCGCGGGCGAACTCGCGCAATACGTGCGCGCCGCAGCCGGT
GCCGCCGTCGTGGCGGTGGCCGTGGGCGCGCAGGACGGCATCACGCCGCCTGCGGCGTGTGAGGAGATTGCCCGGGTCGC
CGGCGTGCCGCTGCAAATCATCGAAGGCGCGGGCCACGCGTCCTACATCGAAACGCCGGACGTTCTGAATGCCGCGCTGG
CCGCGTGGCTCGAACGTATTGCGGCAGGGGAGCGTTGA

Antitoxin


Download         Length: 288 a.a.        Molecular weight: 31311.87 Da        Isoelectric Point: 6.6551

>AT55060 WP_047908838.1 NZ_CP011807:1214550-1215413 [Pandoraea faecigallinarum]
MPADGDDLAEAAPAESRYLVPGLERGLRILTQFSPREPVFSAPELSQRLGIPRTTVFRLLQTLEAMGFLERAGSEKNFRL
GVAVLRLGFEYLSSLELTDLGIPIIERLRDATQLTSHIVIRDGRDIVFVAKAQSVAGVFNSIKVNVGTRLPAHATVHGHV
LMGDLTLAEMRALYPEKTLEKFTPQTPESLGELFERVREDAERGYAVSASSFERGISVVSAPVRNDAGRICAAITVTIPR
ANIDTSMLDAGLIGQVREAADALSHRLNYRPGTDGQTTPYMKSLGLK

Download         Length: 864 bp

>AT55060 NZ_CP011807:1214550-1215413 [Pandoraea faecigallinarum]
TTGCCGGCCGATGGCGACGACCTCGCCGAAGCCGCACCTGCCGAATCCCGCTATCTCGTGCCGGGGCTCGAACGCGGCCT
GCGCATCCTGACGCAATTCTCGCCGCGCGAGCCGGTGTTCAGCGCGCCGGAACTGTCGCAGCGTCTGGGCATTCCGCGCA
CGACGGTCTTTCGCCTGTTGCAGACGCTCGAAGCCATGGGGTTCCTGGAGCGCGCCGGCAGCGAAAAAAACTTCCGTCTG
GGTGTGGCCGTGCTGCGTCTGGGCTTCGAGTACCTCAGTTCGCTGGAATTGACCGATCTGGGCATTCCCATCATCGAGCG
TCTGCGCGACGCCACGCAACTGACCTCGCACATTGTGATCCGCGACGGCCGCGACATCGTGTTCGTGGCGAAGGCGCAGA
GCGTGGCGGGCGTCTTCAATTCGATCAAGGTCAACGTCGGCACGCGCCTGCCGGCGCATGCCACCGTGCACGGTCACGTG
CTGATGGGCGATCTGACGCTCGCCGAAATGCGTGCCCTGTACCCGGAAAAGACACTGGAGAAATTCACGCCGCAAACCCC
CGAGTCGCTGGGCGAACTGTTCGAGCGCGTGCGAGAAGATGCCGAGCGCGGCTACGCGGTGTCGGCGTCGTCGTTCGAGC
GCGGCATCAGCGTGGTGAGCGCACCGGTGCGCAACGACGCGGGGCGCATTTGCGCCGCGATCACCGTCACGATTCCGCGC
GCCAACATCGATACGTCGATGCTCGACGCGGGATTGATCGGCCAGGTGCGCGAGGCGGCGGATGCGCTCTCGCATCGCCT
GAACTACCGGCCCGGCACCGACGGCCAGACCACCCCCTACATGAAGTCACTGGGATTGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3WY29

Antitoxin

Source ID Structure

References