Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2663545..2663816 Replicon chromosome
Accession NZ_CP010439
Organism Escherichia coli K-12 strain K-12 MG1655

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2663583..2663686 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2663545..2663816 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH02_RS13275 2660702..2662141 + 1440 Protein_2512 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SH02_RS13280 2662259..2662495 + 237 WP_001295499.1 DUF1480 family protein -
SH02_RS13285 2662600..2662791 + 192 WP_000457842.1 YebW family protein -
SH02_RS13290 2662792..2663448 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2663545..2663816 + 272 - - Antitoxin
- 2663583..2663686 - 104 - - Toxin
SH02_RS13300 2663844..2664185 - 342 WP_000976476.1 YebY family protein -
SH02_RS13305 2664198..2665070 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
SH02_RS13310 2665074..2665448 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SH02_RS13315 2665587..2665817 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SH02_RS13320 2665919..2666575 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
SH02_RS13325 2666599..2667261 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52470 NZ_CP010439:c2663686-2663583 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52470 NZ_CP010439:2663545-2663816 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References