Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1509077..1509348 Replicon chromosome
Accession NZ_CP010228
Organism Escherichia coli strain S3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1509207..1509310 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1509077..1509348 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG65_RS07875 1505632..1506294 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG65_RS07880 1506318..1506974 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG65_RS07885 1507076..1507306 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG65_RS07890 1507445..1507819 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG65_RS07895 1507823..1508695 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG65_RS07900 1508708..1509049 + 342 WP_000976492.1 YebY family protein -
- 1509077..1509348 - 272 - - Antitoxin
- 1509207..1509310 + 104 - - Toxin
RG65_RS07910 1509445..1510101 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
RG65_RS07915 1510102..1510293 - 192 WP_001296140.1 YebW family protein -
RG65_RS07920 1510398..1510634 - 237 WP_001295499.1 DUF1480 family protein -
RG65_RS07925 1510752..1512191 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51522 NZ_CP010228:1509207-1509310 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51522 NZ_CP010228:c1509348-1509077 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References