Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1380993..1381227 Replicon chromosome
Accession NZ_CP010206
Organism Escherichia coli strain M11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1381123..1381226 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1380993..1381227 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG60_RS07015 1377548..1378210 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG60_RS07020 1378234..1378890 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG60_RS07025 1378992..1379222 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG60_RS07030 1379361..1379735 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG60_RS07035 1379739..1380611 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG60_RS07040 1380624..1380965 + 342 WP_000976492.1 YebY family protein -
- 1380993..1381227 - 235 - - Antitoxin
- 1381123..1381226 + 104 - - Toxin
RG60_RS07050 1381358..1382434 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
RG60_RS07055 1382400..1382681 - 282 WP_001311878.1 excisionase -
RG60_RS07060 1382788..1382976 - 189 WP_001356607.1 DUF1187 family protein -
- 1382792..1382970 + 179 NuclAT_0 - -
- 1382792..1382970 + 179 NuclAT_0 - -
- 1382792..1382970 + 179 NuclAT_0 - -
- 1382792..1382970 + 179 NuclAT_0 - -
RG60_RS07065 1382969..1383163 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
RG60_RS07070 1383220..1384029 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1377548..1439419 61871


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51358 NZ_CP010206:1381123-1381226 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT51358 NZ_CP010206:c1381227-1380993 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References