Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
Location | 1830406..1830640 | Replicon | chromosome |
Accession | NZ_CP010186 | ||
Organism | Escherichia coli strain M6 |
Toxin (RNA)
Gene name | SdsR | ||
Locus tag | - | ||
Coordinates | 1830407..1830510 (-) |
Antitoxin (RNA)
Gene name | RyeA | ||
Locus tag | - | ||
Coordinates | 1830406..1830640 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RG56_RS09705 | 1827604..1828413 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
RG56_RS09710 | 1828470..1828664 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
RG56_RS09715 | 1828657..1828845 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
- | 1828663..1828841 | - | 179 | NuclAT_0 | - | - |
- | 1828663..1828841 | - | 179 | NuclAT_0 | - | - |
- | 1828663..1828841 | - | 179 | NuclAT_0 | - | - |
- | 1828663..1828841 | - | 179 | NuclAT_0 | - | - |
RG56_RS09720 | 1828952..1829233 | + | 282 | WP_001311878.1 | excisionase | - |
RG56_RS09725 | 1829199..1830275 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
- | 1830406..1830640 | + | 235 | - | - | Antitoxin |
- | 1830407..1830510 | - | 104 | - | - | Toxin |
RG56_RS09735 | 1830668..1831009 | - | 342 | WP_000976492.1 | YebY family protein | - |
RG56_RS09740 | 1831022..1831894 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
RG56_RS09745 | 1831898..1832272 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
RG56_RS09750 | 1832411..1832641 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
RG56_RS09755 | 1832743..1833399 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein | - |
RG56_RS09760 | 1833423..1834085 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1777594..1836149 | 58555 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T51243 NZ_CP010186:c1830510-1830407 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT51243 NZ_CP010186:1830406-1830640 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT