Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1830406..1830640 Replicon chromosome
Accession NZ_CP010186
Organism Escherichia coli strain M6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1830407..1830510 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1830406..1830640 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG56_RS09705 1827604..1828413 + 810 WP_000166317.1 recombination protein RecT -
RG56_RS09710 1828470..1828664 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
RG56_RS09715 1828657..1828845 + 189 WP_001356607.1 DUF1187 family protein -
- 1828663..1828841 - 179 NuclAT_0 - -
- 1828663..1828841 - 179 NuclAT_0 - -
- 1828663..1828841 - 179 NuclAT_0 - -
- 1828663..1828841 - 179 NuclAT_0 - -
RG56_RS09720 1828952..1829233 + 282 WP_001311878.1 excisionase -
RG56_RS09725 1829199..1830275 + 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
- 1830406..1830640 + 235 - - Antitoxin
- 1830407..1830510 - 104 - - Toxin
RG56_RS09735 1830668..1831009 - 342 WP_000976492.1 YebY family protein -
RG56_RS09740 1831022..1831894 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG56_RS09745 1831898..1832272 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG56_RS09750 1832411..1832641 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG56_RS09755 1832743..1833399 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG56_RS09760 1833423..1834085 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1777594..1836149 58555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51243 NZ_CP010186:c1830510-1830407 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT51243 NZ_CP010186:1830406-1830640 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References