Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4705064..4705335 Replicon chromosome
Accession NZ_CP010134
Organism Escherichia coli strain D1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4705102..4705205 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4705064..4705335 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG34_RS24595 4702221..4703660 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG34_RS24600 4703778..4704014 + 237 WP_001295499.1 DUF1480 family protein -
RG34_RS24605 4704119..4704310 + 192 WP_001296140.1 YebW family protein -
RG34_RS24610 4704311..4704967 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 4705064..4705335 + 272 - - Antitoxin
- 4705102..4705205 - 104 - - Toxin
RG34_RS24620 4705363..4705704 - 342 WP_000976492.1 YebY family protein -
RG34_RS24625 4705717..4706589 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG34_RS24630 4706593..4706967 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG34_RS24635 4707106..4707336 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG34_RS24640 4707438..4708094 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG34_RS24645 4708118..4708780 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50657 NZ_CP010134:c4705205-4705102 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50657 NZ_CP010134:4705064-4705335 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References