Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2046839..2047110 Replicon chromosome
Accession NZ_CP010129
Organism Escherichia coli strain C9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2046969..2047072 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2046839..2047110 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG31_RS10900 2043394..2044056 - 663 WP_000944258.1 exodeoxyribonuclease X -
RG31_RS10905 2044080..2044736 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG31_RS10910 2044838..2045068 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG31_RS10915 2045207..2045581 + 375 WP_000168747.1 CopC domain-containing protein YobA -
RG31_RS10920 2045585..2046457 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
RG31_RS10925 2046470..2046811 + 342 WP_072651707.1 YebY family protein -
- 2046839..2047110 - 272 - - Antitoxin
- 2046969..2047072 + 104 - - Toxin
RG31_RS10935 2047207..2047863 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
RG31_RS10940 2047864..2048055 - 192 WP_001338167.1 YebW family protein -
RG31_RS10945 2048160..2048396 - 237 WP_001338166.1 DUF1480 family protein -
RG31_RS10950 2048514..2049953 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50567 NZ_CP010129:2046969-2047072 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50567 NZ_CP010129:c2047110-2046839 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References