Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2468058..2468329 Replicon chromosome
Accession NZ_CP010125
Organism Escherichia coli strain C8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2468096..2468199 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2468058..2468329 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG30_RS12780 2465215..2466654 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG30_RS12785 2466772..2467008 + 237 WP_001295499.1 DUF1480 family protein -
RG30_RS12790 2467113..2467304 + 192 WP_000457842.1 YebW family protein -
RG30_RS12795 2467305..2467961 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2468058..2468329 + 272 - - Antitoxin
- 2468096..2468199 - 104 - - Toxin
RG30_RS12805 2468357..2468698 - 342 WP_000976492.1 YebY family protein -
RG30_RS12810 2468711..2469583 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG30_RS12815 2469587..2469961 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG30_RS12820 2470100..2470330 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG30_RS12825 2470432..2471088 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG30_RS12830 2471112..2471774 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50536 NZ_CP010125:c2468199-2468096 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50536 NZ_CP010125:2468058-2468329 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References