Detailed information of TA system TA050279

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2069895..2070141
• Replicon: chromosome
• Accession: NZ_CP010052
• Organism: Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: QU35_RS22720
• Protein ID: WP_109789044.1
• Coordinates: 2069895..2069987 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2069968..2070141 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QU35_RS10025	2065054..2065389	+	336	WP_009967409.1	hypothetical protein	-
QU35_RS10030	2065436..2069041	-	3606	WP_004399367.1	membrane protein	-
QU35_RS10035	2069274..2069606	-	333	WP_026009814.1	hypothetical protein	-
QU35_RS22720	2069895..2069987	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2069968..2070141	-	174	-	-	Antitoxin
QU35_RS10040	2070256..2071098	-	843	WP_003231327.1	hypothetical protein	-
QU35_RS10045	2071298..2071756	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
QU35_RS10050	2071766..2073568	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
QU35_RS10055	2073670..2074227	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2003413..2116682	113269

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T50279 WP_109789044.1 NZ_CP010052:2069895-2069987 [Bacillus subtilis subsp. subtilis str. 168]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T50279 NZ_CP010052:2069895-2069987 [Bacillus subtilis subsp. subtilis str. 168]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT50279 NZ_CP010052:c2070141-2069968 [Bacillus subtilis subsp. subtilis str. 168]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin