Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2725309..2725510 Replicon chromosome
Accession NZ_CP009854
Organism UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2725314..2725417 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2725309..2725510 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECNIH5_RS12820 (ECNIH5_12820) 2721571..2723019 + 1449 WP_227022505.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECNIH5_RS12825 (ECNIH5_12825) 2723124..2723363 + 240 WP_006811010.1 YebV family protein -
ECNIH5_RS12830 (ECNIH5_12830) 2723398..2724042 - 645 WP_038416258.1 protein-serine/threonine phosphatase -
ECNIH5_RS12835 (ECNIH5_12835) 2724210..2725190 + 981 WP_038416259.1 VirK/YbjX family protein -
ECNIH5_RS24125 2725236..2725433 + 198 WP_071881497.1 hypothetical protein -
- 2725309..2725510 + 202 - - Antitoxin
- 2725314..2725417 - 104 - - Toxin
ECNIH5_RS12840 (ECNIH5_12840) 2725559..2725897 - 339 WP_022648464.1 YebY family protein -
ECNIH5_RS12845 (ECNIH5_12845) 2725914..2726783 - 870 WP_038416260.1 copper homeostasis membrane protein CopD -
ECNIH5_RS12850 (ECNIH5_12850) 2726785..2727156 - 372 WP_038416261.1 CopC domain-containing protein YobA -
ECNIH5_RS12855 (ECNIH5_12855) 2727294..2727524 + 231 WP_003859784.1 DNA polymerase III subunit theta -
ECNIH5_RS12860 (ECNIH5_12860) 2727636..2728274 + 639 WP_022648467.1 nitrilase-related carbon-nitrogen hydrolase -
ECNIH5_RS12865 (ECNIH5_12865) 2728299..2728961 + 663 WP_022648468.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T49993 NZ_CP009854:c2725417-2725314 [Enterobacter cloacae]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT49993 NZ_CP009854:2725309-2725510 [Enterobacter cloacae]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGGCGTCAGGTTTTCCAGTCCACAGTAAAAGTGGT
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References