Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 434367..434998 Replicon chromosome
Accession NZ_CP009571
Organism Sphingomonas taxi strain ATCC 55669

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MC45_RS01915 Protein ID WP_038658838.1
Coordinates 434591..434998 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MC45_RS01910 Protein ID WP_038658835.1
Coordinates 434367..434594 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MC45_RS01890 429407..431200 + 1794 WP_052075473.1 methyl-accepting chemotaxis protein -
MC45_RS01895 431323..431712 + 390 WP_038658827.1 MerC domain-containing protein -
MC45_RS01900 431754..432221 + 468 WP_038658829.1 transcriptional repressor -
MC45_RS01905 432275..434200 + 1926 WP_038658832.1 1-deoxy-D-xylulose-5-phosphate synthase -
MC45_RS19470 434197..434349 + 153 WP_169742513.1 hypothetical protein -
MC45_RS01910 434367..434594 + 228 WP_038658835.1 hypothetical protein Antitoxin
MC45_RS01915 434591..434998 + 408 WP_038658838.1 PIN domain-containing protein Toxin
MC45_RS01920 435008..435679 - 672 WP_038658841.1 alpha/beta hydrolase -
MC45_RS01925 435883..436617 + 735 WP_038658844.1 TlyA family RNA methyltransferase -
MC45_RS01930 436707..437258 + 552 WP_169742514.1 tryptophan-rich sensory protein -
MC45_RS01935 437291..437575 + 285 WP_038658846.1 accessory factor UbiK family protein -
MC45_RS01940 437672..438175 + 504 WP_038658848.1 YbjN domain-containing protein -
MC45_RS01945 438175..438969 + 795 WP_038658851.1 NAD(P)-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-116)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14921.46 Da        Isoelectric Point: 6.6261

>T49290 WP_038658838.1 NZ_CP009571:434591-434998 [Sphingomonas taxi]
VSAGFLDTNVLLYGFTADDHRQPEAMRLIRAGCVISVQCLNECAFVARRKLRMTWAEIADPLAIIVQLSRPVMPVTIDLH
RLGIHLAERYTLSVYDGMIAAAAVIAGCDILYSEDMHHGLFIDGRVRIVNPFAPA

Download         Length: 408 bp

>T49290 NZ_CP009571:434591-434998 [Sphingomonas taxi]
GTGAGCGCCGGCTTTCTCGATACGAATGTCCTTCTTTACGGCTTTACCGCTGACGATCATCGACAGCCCGAGGCGATGCG
TCTTATTCGCGCGGGTTGCGTAATCAGCGTTCAGTGCTTGAATGAATGTGCGTTCGTCGCCCGGCGCAAACTCCGCATGA
CTTGGGCGGAGATCGCCGACCCCCTTGCGATCATTGTGCAATTGAGCCGTCCGGTCATGCCGGTTACGATCGACCTCCAT
CGGCTCGGGATACATCTCGCCGAACGCTACACCCTGTCCGTCTACGACGGGATGATCGCGGCGGCAGCCGTCATCGCCGG
GTGCGACATTCTCTATTCCGAAGACATGCACCACGGCCTCTTCATCGACGGACGCGTCAGGATCGTGAACCCCTTCGCGC
CCGCCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8272.43 Da        Isoelectric Point: 4.6158

>AT49290 WP_038658835.1 NZ_CP009571:434367-434594 [Sphingomonas taxi]
MKLTRSPDGYVVRVPADLVAALDLHEGDDVTIGKIEEMSCDLSEAEKDALVARMKSLARPLPPGFKFDREEANSR

Download         Length: 228 bp

>AT49290 NZ_CP009571:434367-434594 [Sphingomonas taxi]
ATGAAGCTGACGAGATCTCCTGACGGGTATGTAGTCCGGGTGCCGGCCGATCTGGTTGCGGCTCTCGACTTGCATGAAGG
CGACGACGTAACGATTGGGAAGATCGAAGAAATGTCGTGCGACTTGTCCGAAGCCGAGAAGGACGCCCTCGTTGCACGAA
TGAAGTCTCTGGCGAGACCGTTGCCGCCCGGTTTTAAATTCGATCGCGAGGAAGCGAACTCCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References