Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 360578..361113 Replicon chromosome
Accession NZ_CP009364
Organism Yersinia frederiksenii Y225

Toxin (Protein)


Gene name relE Uniprot ID A0A386HCD1
Locus tag AW19_RS02055 Protein ID WP_038635036.1
Coordinates 360826..361113 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A386HCJ9
Locus tag AW19_RS02050 Protein ID WP_038635039.1
Coordinates 360578..360829 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AW19_RS02025 356049..356552 + 504 WP_038635051.1 ferredoxin-type protein NapF -
AW19_RS02030 356542..356808 + 267 WP_019081761.1 chaperone NapD -
AW19_RS02035 356805..359300 + 2496 WP_038635047.1 nitrate reductase catalytic subunit NapA -
AW19_RS02040 359335..359802 + 468 WP_038635044.1 nitrate reductase cytochrome c-type subunit -
AW19_RS02045 359830..360429 + 600 WP_038635042.1 cytochrome c-type protein NapC -
AW19_RS02050 360578..360829 + 252 WP_038635039.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AW19_RS02055 360826..361113 + 288 WP_038635036.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AW19_RS02060 361142..361717 + 576 WP_038635033.1 GDP-mannose pyrophosphatase NudK -
AW19_RS02065 361942..364221 + 2280 WP_038635031.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
AW19_RS02070 364372..364845 - 474 WP_038635028.1 YaiI/YqxD family protein -
AW19_RS02075 364845..365771 - 927 WP_038635025.1 oxygen-dependent coproporphyrinogen oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11215.24 Da        Isoelectric Point: 10.3200

>T48808 WP_038635036.1 NZ_CP009364:360826-361113 [Yersinia frederiksenii Y225]
MIYTVKFREEALKEWHKLDKTIQQQFAKKLKKCSDNPHIESAKLRGMKDCYKIKLRSSGFRLVYEVIDDILIVAVVAVGK
RERSEVYKLASERLR

Download         Length: 288 bp

>T48808 NZ_CP009364:360826-361113 [Yersinia frederiksenii Y225]
ATGATCTATACCGTTAAGTTCAGAGAAGAAGCGCTAAAGGAATGGCACAAACTGGATAAGACGATACAACAGCAGTTCGC
CAAAAAATTAAAAAAGTGCAGCGATAATCCACATATTGAGAGTGCTAAACTACGTGGGATGAAAGACTGTTACAAAATTA
AATTACGGTCCTCAGGTTTCCGACTAGTGTATGAAGTTATTGATGATATTTTGATAGTTGCTGTGGTTGCAGTAGGAAAA
AGAGAACGTAGCGAGGTTTATAAACTTGCCAGTGAAAGATTACGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9191.43 Da        Isoelectric Point: 4.1947

>AT48808 WP_038635039.1 NZ_CP009364:360578-360829 [Yersinia frederiksenii Y225]
MPSVILSDTSASVSELKKNPMATVNAGAGFPVAILNRNQPAFYCVPAELYEQIMEALDDNELAKLVNERRNQPLHDIDLE
SYL

Download         Length: 252 bp

>AT48808 NZ_CP009364:360578-360829 [Yersinia frederiksenii Y225]
ATGCCAAGTGTAATTTTGTCAGATACTAGCGCGAGTGTGAGTGAACTGAAGAAAAATCCCATGGCGACAGTGAATGCCGG
AGCTGGTTTCCCTGTTGCTATCCTGAACCGTAATCAACCTGCGTTTTATTGTGTGCCTGCTGAACTTTATGAACAAATAA
TGGAAGCGCTTGACGATAATGAATTGGCTAAGTTGGTTAACGAACGTCGTAACCAACCACTTCATGATATTGATTTGGAA
AGCTATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References