Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2124546..2124817 Replicon chromosome
Accession NZ_CP009166
Organism Escherichia coli 1303

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2124584..2124687 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2124546..2124817 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC1303_RS10460 2121703..2123142 + 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EC1303_RS10465 2123260..2123496 + 237 WP_001338166.1 DUF1480 family protein -
EC1303_RS10470 2123601..2123792 + 192 WP_001338167.1 YebW family protein -
EC1303_RS10475 2123793..2124449 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 2124546..2124817 + 272 - - Antitoxin
- 2124584..2124687 - 104 - - Toxin
EC1303_RS10485 2124845..2125186 - 342 WP_000976472.1 YebY family protein -
EC1303_RS10490 2125199..2126071 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EC1303_RS10495 2126075..2126449 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EC1303_RS10500 2126588..2126818 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EC1303_RS10505 2126920..2127576 + 657 WP_041124109.1 carbon-nitrogen hydrolase family protein -
EC1303_RS10510 2127600..2128262 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T48514 NZ_CP009166:c2124687-2124584 [Escherichia coli 1303]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT48514 NZ_CP009166:2124546-2124817 [Escherichia coli 1303]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References