Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1762808..1763422 Replicon chromosome
Accession NZ_CP007506
Organism Pandoraea pnomenusa strain RB38

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DA70_RS07820 Protein ID WP_025249432.1
Coordinates 1763126..1763422 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DA70_RS07815 Protein ID WP_025249433.1
Coordinates 1762808..1763122 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA70_RS07785 1758024..1759937 + 1914 WP_025249438.1 selenocysteine-specific translation elongation factor -
DA70_RS07795 1760125..1760442 - 318 WP_029754174.1 tyrosine-type recombinase/integrase -
DA70_RS24490 1760656..1760841 + 186 WP_144347378.1 hypothetical protein -
DA70_RS07800 1760845..1761309 + 465 WP_025249436.1 lysozyme -
DA70_RS24495 1761339..1761680 + 342 WP_150646730.1 hypothetical protein -
DA70_RS07810 1762007..1762798 + 792 WP_025249434.1 DNA adenine methylase -
DA70_RS07815 1762808..1763122 - 315 WP_025249433.1 putative addiction module antidote protein Antitoxin
DA70_RS07820 1763126..1763422 - 297 WP_025249432.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DA70_RS07825 1763830..1764510 + 681 WP_155734178.1 hypothetical protein -
DA70_RS07830 1764721..1765479 + 759 WP_155734179.1 hypothetical protein -
DA70_RS07835 1765634..1766161 - 528 WP_196759349.1 hypothetical protein -
DA70_RS07840 1766248..1767273 - 1026 WP_025249428.1 ParA family protein -
DA70_RS24500 1767556..1767927 - 372 WP_155734180.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10762.49 Da        Isoelectric Point: 10.2130

>T46568 WP_025249432.1 NZ_CP007506:c1763422-1763126 [Pandoraea pnomenusa]
MTKILQHPEFSKWFSGLRDRRGVAAIAQRLDRLALGNPGNVKPVGEGVSELKIDVGPGYRVYFVQRGAVLVVLLCGGDKS
TQAKDIKRAKKLADELED

Download         Length: 297 bp

>T46568 NZ_CP007506:c1763422-1763126 [Pandoraea pnomenusa]
ATGACGAAAATTCTCCAACACCCCGAGTTCAGCAAATGGTTTTCCGGCCTGCGTGATCGCAGGGGCGTCGCAGCCATCGC
TCAACGGCTCGACCGCCTGGCGCTCGGGAATCCCGGTAACGTAAAGCCGGTCGGCGAGGGTGTTTCGGAATTGAAGATCG
ACGTCGGCCCCGGCTATCGCGTCTACTTTGTTCAGCGCGGGGCCGTGCTGGTTGTCCTGCTGTGCGGTGGCGACAAGTCG
ACGCAAGCCAAGGACATCAAGCGCGCGAAGAAGCTGGCCGACGAACTGGAGGACTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11177.67 Da        Isoelectric Point: 4.8782

>AT46568 WP_025249433.1 NZ_CP007506:c1763122-1762808 [Pandoraea pnomenusa]
MKLSELKEFDAAEALKDDETIKHYLSLAFEGGDSREIQRALGTVARARGMSALARESGIAREALYRALSDTGNPEFATIM
KVLGALGLHLTLAPNTESPDTITA

Download         Length: 315 bp

>AT46568 NZ_CP007506:c1763122-1762808 [Pandoraea pnomenusa]
ATGAAACTAAGCGAACTGAAGGAATTTGACGCCGCAGAGGCGCTGAAGGACGACGAGACGATCAAGCACTACCTTTCGCT
CGCGTTTGAAGGTGGGGATTCTCGCGAAATTCAACGGGCGCTCGGCACCGTCGCCCGCGCTCGCGGGATGAGCGCCCTTG
CCCGCGAGTCTGGCATCGCTCGCGAAGCACTGTATCGCGCGCTGTCCGACACGGGCAATCCGGAATTCGCAACCATCATG
AAGGTGCTGGGCGCACTTGGCCTGCACCTCACGCTGGCTCCGAATACCGAATCGCCCGATACGATCACGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References