Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 876038..876713 Replicon chromosome
Accession NZ_CP007448
Organism Yersinia enterocolitica LC20

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LC20_RS04215 Protein ID WP_025377115.1
Coordinates 876038..876466 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LC20_RS04220 Protein ID WP_025377116.1
Coordinates 876447..876713 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LC20_RS04195 871823..872341 + 519 WP_025377111.1 flavodoxin FldB -
LC20_RS04200 872391..873812 - 1422 WP_025377112.1 cell envelope integrity protein CreD -
LC20_RS04205 873905..875332 - 1428 WP_025377113.1 two-component system sensor histidine kinase CreC -
LC20_RS04210 875343..876041 - 699 WP_025377114.1 two-component system response regulator CreB -
LC20_RS04215 876038..876466 - 429 WP_025377115.1 protein YgfX Toxin
LC20_RS04220 876447..876713 - 267 WP_025377116.1 FAD assembly factor SdhE Antitoxin
LC20_RS04225 876978..877970 + 993 WP_025377117.1 tRNA-modifying protein YgfZ -
LC20_RS04230 878025..878714 - 690 WP_025377118.1 hemolysin III family protein -
LC20_RS04235 878926..879528 + 603 WP_025377119.1 HD domain-containing protein -
LC20_RS04240 879541..880290 - 750 WP_025377120.1 SDR family oxidoreductase -
LC20_RS04245 880389..881081 - 693 WP_025377121.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 16585.56 Da        Isoelectric Point: 10.2688

>T46448 WP_025377115.1 NZ_CP007448:c876466-876038 [Yersinia enterocolitica LC20]
VAQWRCDLRVSWHTQLFSLLAHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNIKSCQGEIRLKPGKVVLWKRH
EWIVIKQPWITHYGVLLSLQQTSSRSTRKRLWLAADSMSEEEWRQLCLLLRHSFGVDKGINE

Download         Length: 429 bp

>T46448 NZ_CP007448:c876466-876038 [Yersinia enterocolitica LC20]
GTGGCCCAGTGGCGATGTGACCTGCGGGTATCCTGGCACACTCAACTCTTCTCTTTATTAGCGCATGGCGTCTTGGTAAT
ACTCACGCTAGTGGCGCCTTGGCCTCAGGGTTATACGGCACTTTGGTTAGTATTGCTGACGTTGGTGGTGTTTGAGTGTA
TCCGCAGCCAGAAAAATATTAAGTCTTGCCAGGGTGAAATCAGGCTGAAACCCGGCAAGGTGGTGCTATGGAAAAGACAT
GAATGGATTGTCATTAAACAGCCCTGGATCACCCATTATGGTGTGTTATTGAGTTTACAACAGACCAGCAGCCGCTCAAC
CCGCAAGCGCTTATGGCTGGCGGCTGACAGTATGTCTGAAGAAGAGTGGCGGCAACTATGCTTGTTATTGCGTCATTCAT
TTGGCGTCGATAAAGGTATCAATGAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10505.98 Da        Isoelectric Point: 5.1405

>AT46448 WP_025377116.1 NZ_CP007448:c876713-876447 [Yersinia enterocolitica LC20]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQSFIRLLECDDPDLFNWLMNHGEPQDNELRQMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT46448 NZ_CP007448:c876713-876447 [Yersinia enterocolitica LC20]
ATGGAAATTGATAATAAAGCCCGCATTCACTGGGCGTGCCGTCGAGGTATGCGCGAACTGGATATCTCTATCATGCCGTT
TTTTGAACATGAATATGATGGCTTGAGTGACAACGAGAAACAGAGCTTTATCCGTTTACTTGAATGCGATGATCCAGACT
TATTTAACTGGCTGATGAATCACGGGGAGCCGCAGGACAACGAACTGCGTCAAATGGTCAAACTGATTCAAACACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References