Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2678031..2678299 Replicon chromosome
Accession NZ_CP007394
Organism Escherichia coli strain ST2747

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2678069..2678172 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2678031..2678299 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CF60_RS12945 2675188..2676627 + 1440 WP_025210565.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CF60_RS12950 2676745..2676981 + 237 WP_025210566.1 DUF1480 family protein -
CF60_RS12955 2677086..2677277 + 192 WP_001296140.1 YebW family protein -
CF60_RS12960 2677278..2677934 - 657 WP_025210567.1 protein-serine/threonine phosphatase -
- 2678031..2678299 + 269 - - Antitoxin
- 2678069..2678172 - 104 - - Toxin
CF60_RS12970 2678329..2678670 - 342 WP_000976472.1 YebY family protein -
CF60_RS12975 2678683..2679555 - 873 WP_025210568.1 copper homeostasis membrane protein CopD -
CF60_RS12980 2679559..2679933 - 375 WP_000168745.1 CopC domain-containing protein YobA -
CF60_RS12985 2680072..2680302 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CF60_RS12990 2680404..2681060 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
CF60_RS12995 2681084..2681746 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2669801..2685611 15810


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T46392 NZ_CP007394:c2678172-2678069 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT46392 NZ_CP007394:2678031-2678299 [Escherichia coli]
AAAGTCAGCGAAAGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References