Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2728632..2728900 Replicon chromosome
Accession NZ_CP007392
Organism Escherichia coli strain ST2747

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2728670..2728773 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2728632..2728900 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CF58_RS13190 2725789..2727228 + 1440 WP_025210565.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CF58_RS13195 2727346..2727582 + 237 WP_025210566.1 DUF1480 family protein -
CF58_RS13200 2727687..2727878 + 192 WP_001296140.1 YebW family protein -
CF58_RS13205 2727879..2728535 - 657 WP_025210567.1 protein-serine/threonine phosphatase -
- 2728632..2728900 + 269 - - Antitoxin
- 2728670..2728773 - 104 - - Toxin
CF58_RS13215 2728930..2729271 - 342 WP_000976472.1 YebY family protein -
CF58_RS13220 2729284..2730156 - 873 WP_025210568.1 copper homeostasis membrane protein CopD -
CF58_RS13225 2730160..2730534 - 375 WP_000168745.1 CopC domain-containing protein YobA -
CF58_RS13230 2730673..2730903 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CF58_RS13235 2731005..2731661 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
CF58_RS13240 2731685..2732347 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2720402..2753398 32996


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T46334 NZ_CP007392:c2728773-2728670 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT46334 NZ_CP007392:2728632-2728900 [Escherichia coli]
AAAGTCAGCGAAAGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References