Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2301348..2301616 Replicon chromosome
Accession NZ_CP006027
Organism Escherichia coli O145:H28 str. RM13514

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2301386..2301489 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2301348..2301616 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECRM13514_RS11730 2298505..2299944 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECRM13514_RS11735 2300062..2300298 + 237 WP_001295499.1 DUF1480 family protein -
ECRM13514_RS11740 2300403..2300594 + 192 WP_001313035.1 YebW family protein -
ECRM13514_RS11745 2300595..2301251 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 2301348..2301616 + 269 - - Antitoxin
- 2301386..2301489 - 104 - - Toxin
ECRM13514_RS11755 2301646..2301987 - 342 WP_000976475.1 YebY family protein -
ECRM13514_RS11760 2302000..2302872 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
ECRM13514_RS11765 2302876..2303250 - 375 WP_000168738.1 CopC domain-containing protein YobA -
ECRM13514_RS11770 2303389..2303619 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECRM13514_RS11775 2303721..2304377 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ECRM13514_RS11780 2304401..2305063 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T45172 NZ_CP006027:c2301489-2301386 [Escherichia coli O145:H28 str. RM13514]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT45172 NZ_CP006027:2301348-2301616 [Escherichia coli O145:H28 str. RM13514]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References