Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1338247..1338688 Replicon chromosome
Accession NZ_AP028062
Organism Marinobacter shengliensis strain D49

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QUE75_RS06220 Protein ID WP_286254415.1
Coordinates 1338542..1338688 (-) Length 49 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QUE75_RS06215 Protein ID WP_286254413.1
Coordinates 1338247..1338552 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE75_RS06195 (MAALD49_12250) 1334540..1335304 - 765 WP_286254405.1 class III extradiol ring-cleavage dioxygenase -
QUE75_RS06200 (MAALD49_12260) 1335342..1335782 - 441 WP_286254407.1 DoxX family protein -
QUE75_RS06205 (MAALD49_12270) 1335892..1336782 + 891 WP_286254409.1 LysR family transcriptional regulator -
QUE75_RS06210 (MAALD49_12280) 1336820..1338097 + 1278 WP_286254411.1 MFS transporter -
QUE75_RS06215 (MAALD49_12290) 1338247..1338552 - 306 WP_286254413.1 CopG family transcriptional regulator Antitoxin
QUE75_RS06220 (MAALD49_12300) 1338542..1338688 - 147 WP_286254415.1 BrnT family toxin Toxin
QUE75_RS06225 (MAALD49_12310) 1338945..1339196 + 252 WP_286254417.1 hypothetical protein -
QUE75_RS06230 1339633..1340615 - 983 Protein_1222 transposase -
QUE75_RS06235 (MAALD49_12350) 1340677..1341402 - 726 WP_286254418.1 hypothetical protein -
QUE75_RS06240 (MAALD49_12360) 1341654..1341818 - 165 WP_286254420.1 hypothetical protein -
QUE75_RS06245 (MAALD49_12370) 1341910..1342092 - 183 WP_286254422.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-42)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 49 a.a.        Molecular weight: 5593.24 Da        Isoelectric Point: 4.1947

>T44460 WP_286254415.1 NZ_AP028062:c1338688-1338542 [Marinobacter shengliensis]
MDEFEFDEAKSQANLDKHGIDFVAAQRLCKDPYLLEIRAKSEVELYES

Download         Length: 147 bp

>T44460 NZ_AP028062:c1338688-1338542 [Marinobacter shengliensis]
ATGGATGAATTTGAATTCGACGAAGCAAAAAGCCAGGCCAATCTGGATAAGCACGGTATTGATTTCGTTGCTGCCCAGAG
GCTGTGTAAAGATCCATACCTGCTGGAGATCCGCGCAAAATCGGAGGTTGAGCTCTATGAAAGCTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11497.91 Da        Isoelectric Point: 4.9328

>AT44460 WP_286254413.1 NZ_AP028062:c1338552-1338247 [Marinobacter shengliensis]
MKAKNFDKKFEEGQEDIIDDLDLSSVRRVIDDLDLSSVRRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLV
ERLQAESANKRLNGDTAGGAN

Download         Length: 306 bp

>AT44460 NZ_AP028062:c1338552-1338247 [Marinobacter shengliensis]
ATGAAAGCTAAAAACTTCGACAAAAAATTTGAGGAAGGTCAGGAAGACATTATTGATGACCTGGACCTGTCCTCTGTTCG
CCGCGTTATTGATGACCTGGACCTGTCCTCTGTTCGCCGCGTTAATCAGGAACAAAAGCGAATCAACGTCGATTTCCCGG
CTTGGGTTGTCGAGTCTTTGGATCGTGAGGCCGCGCGCATAGGCGTTACCCGTCAATCGATCATCAAGGTGTGGCTGGTG
GAGCGTCTTCAGGCAGAATCTGCTAACAAACGGCTCAATGGTGATACCGCAGGCGGCGCAAATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References