Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 294472..295068 Replicon chromosome
Accession NZ_AP025927
Organism Enterobacter hormaechei strain FUJ80381

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NGK75_RS01405 Protein ID WP_023295756.1
Coordinates 294766..295068 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag NGK75_RS01400 Protein ID WP_023295755.1
Coordinates 294472..294759 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGK75_RS01395 (FJMB80381_02680) 292844..294475 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
NGK75_RS01400 (FJMB80381_02690) 294472..294759 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
NGK75_RS01405 (FJMB80381_02700) 294766..295068 - 303 WP_023295756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NGK75_RS01410 (FJMB80381_02710) 295266..296138 + 873 WP_032646867.1 23S rRNA pseudouridine(2604) synthase RluF -
NGK75_RS01415 (FJMB80381_02720) 296139..296411 - 273 WP_017382612.1 DUF3811 domain-containing protein -
NGK75_RS01420 (FJMB80381_02730) 296462..297406 - 945 WP_032646868.1 ketopantoate/pantoate/pantothenate transporter PanS -
NGK75_RS01425 (FJMB80381_02740) 297500..298849 - 1350 WP_251266326.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11441.24 Da        Isoelectric Point: 10.1042

>T41727 WP_023295756.1 NZ_AP025927:c295068-294766 [Enterobacter hormaechei]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T41727 NZ_AP025927:c295068-294766 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATTC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT41727 WP_023295755.1 NZ_AP025927:c294759-294472 [Enterobacter hormaechei]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp

>AT41727 NZ_AP025927:c294759-294472 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGCTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References