Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1756621..1757534 Replicon chromosome
Accession NZ_AP025855
Organism Enterobacter hormaechei strain FUJ80144

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NGJ60_RS08385 Protein ID WP_032647883.1
Coordinates 1756621..1757094 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NGJ60_RS08390 Protein ID WP_023296216.1
Coordinates 1757091..1757534 (-) Length 148 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGJ60_RS08365 (FJMB80144_16370) 1752780..1754090 + 1311 WP_032647879.1 type I-F CRISPR-associated protein Csy1 -
NGJ60_RS08370 (FJMB80144_16380) 1754087..1755022 + 936 WP_032647880.1 type I-F CRISPR-associated protein Csy2 -
NGJ60_RS08375 (FJMB80144_16390) 1755036..1756034 + 999 WP_032647881.1 type I-F CRISPR-associated protein Csy3 -
NGJ60_RS08380 (FJMB80144_16400) 1756044..1756598 + 555 WP_032647882.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
NGJ60_RS08385 (FJMB80144_16410) 1756621..1757094 - 474 WP_032647883.1 RES domain-containing protein Toxin
NGJ60_RS08390 (FJMB80144_16420) 1757091..1757534 - 444 WP_023296216.1 DUF2384 domain-containing protein Antitoxin
NGJ60_RS08395 (FJMB80144_16430) 1758632..1758850 - 219 WP_002211347.1 translation initiation factor IF-1 -
NGJ60_RS08400 (FJMB80144_16440) 1759135..1759839 - 705 WP_032668747.1 leucyl/phenylalanyl-tRNA--protein transferase -
NGJ60_RS08405 (FJMB80144_16450) 1759885..1761606 - 1722 WP_032647885.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-147)

Antitoxin

(15-147)


Sequences


Toxin        


Download         Length: 158 a.a.        Molecular weight: 17569.96 Da        Isoelectric Point: 5.5555

>T41389 WP_032647883.1 NZ_AP025855:c1757094-1756621 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Download         Length: 474 bp

>T41389 NZ_AP025855:c1757094-1756621 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16512.81 Da        Isoelectric Point: 6.4819

>AT41389 WP_023296216.1 NZ_AP025855:c1757534-1757091 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT41389 NZ_AP025855:c1757534-1757091 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References