Detailed information of TA system TA041370

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1770253..1771166
• Replicon: chromosome
• Accession: NZ_AP025851
• Organism: Enterobacter hormaechei strain FUJ80068

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGJ26_RS08475
• Protein ID: WP_032647883.1
• Coordinates: 1770253..1770726 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGJ26_RS08480
• Protein ID: WP_023296216.1
• Coordinates: 1770723..1771166 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NGJ26_RS08455 (FJMB80068_16620)	1766412..1767722	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
NGJ26_RS08460 (FJMB80068_16630)	1767719..1768654	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
NGJ26_RS08465 (FJMB80068_16640)	1768668..1769666	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
NGJ26_RS08470 (FJMB80068_16650)	1769676..1770230	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
NGJ26_RS08475 (FJMB80068_16660)	1770253..1770726	-	474	WP_032647883.1	RES domain-containing protein	Toxin
NGJ26_RS08480 (FJMB80068_16670)	1770723..1771166	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
NGJ26_RS08485 (FJMB80068_16680)	1772264..1772482	-	219	WP_002211347.1	translation initiation factor IF-1	-
NGJ26_RS08490 (FJMB80068_16690)	1772767..1773471	-	705	WP_032647884.1	leucyl/phenylalanyl-tRNA--protein transferase	-
NGJ26_RS08495 (FJMB80068_16700)	1773517..1775238	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T41370 WP_032647883.1 NZ_AP025851:c1770726-1770253 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T41370 NZ_AP025851:c1770726-1770253 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT41370 WP_023296216.1 NZ_AP025851:c1771166-1770723 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT41370 NZ_AP025851:c1771166-1770723 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA