Detailed information of TA system TA041351

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1770254..1771167
• Replicon: chromosome
• Accession: NZ_AP025847
• Organism: Enterobacter hormaechei strain FUJ80063

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGK57_RS08475
• Protein ID: WP_032647883.1
• Coordinates: 1770254..1770727 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGK57_RS08480
• Protein ID: WP_023296216.1
• Coordinates: 1770724..1771167 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NGK57_RS08455 (FJMB80063_16630)	1766413..1767723	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
NGK57_RS08460 (FJMB80063_16640)	1767720..1768655	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
NGK57_RS08465 (FJMB80063_16650)	1768669..1769667	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
NGK57_RS08470 (FJMB80063_16660)	1769677..1770231	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
NGK57_RS08475 (FJMB80063_16670)	1770254..1770727	-	474	WP_032647883.1	RES domain-containing protein	Toxin
NGK57_RS08480 (FJMB80063_16680)	1770724..1771167	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
NGK57_RS08485 (FJMB80063_16690)	1772265..1772483	-	219	WP_002211347.1	translation initiation factor IF-1	-
NGK57_RS08490 (FJMB80063_16700)	1772768..1773472	-	705	WP_032647884.1	leucyl/phenylalanyl-tRNA--protein transferase	-
NGK57_RS08495 (FJMB80063_16710)	1773518..1775239	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T41351 WP_032647883.1 NZ_AP025847:c1770727-1770254 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T41351 NZ_AP025847:c1770727-1770254 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT41351 WP_023296216.1 NZ_AP025847:c1771167-1770724 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT41351 NZ_AP025847:c1771167-1770724 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA