Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 295540..296136 Replicon chromosome
Accession NZ_AP025847
Organism Enterobacter hormaechei strain FUJ80063

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NGK57_RS01410 Protein ID WP_023295756.1
Coordinates 295834..296136 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag NGK57_RS01405 Protein ID WP_023295755.1
Coordinates 295540..295827 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGK57_RS01400 (FJMB80063_02680) 293912..295543 + 1632 WP_251268099.1 Na/Pi cotransporter family protein -
NGK57_RS01405 (FJMB80063_02690) 295540..295827 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
NGK57_RS01410 (FJMB80063_02700) 295834..296136 - 303 WP_023295756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NGK57_RS01415 (FJMB80063_02710) 296334..297206 + 873 WP_032646867.1 23S rRNA pseudouridine(2604) synthase RluF -
NGK57_RS01420 (FJMB80063_02720) 297207..297479 - 273 WP_017382612.1 DUF3811 domain-containing protein -
NGK57_RS01425 (FJMB80063_02730) 297530..298474 - 945 WP_032646868.1 ketopantoate/pantoate/pantothenate transporter PanS -
NGK57_RS01430 (FJMB80063_02740) 298568..299917 - 1350 WP_006810501.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11441.24 Da        Isoelectric Point: 10.1042

>T41347 WP_023295756.1 NZ_AP025847:c296136-295834 [Enterobacter hormaechei]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T41347 NZ_AP025847:c296136-295834 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATTC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT41347 WP_023295755.1 NZ_AP025847:c295827-295540 [Enterobacter hormaechei]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp

>AT41347 NZ_AP025847:c295827-295540 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGCTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References